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Drp2 dystrophin related protein 2 [ Mus caroli (Ryukyu mouse) ]

Gene ID: 110286576, updated on 15-Mar-2024

Summary

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Gene symbol
Drp2
Gene description
dystrophin related protein 2
See related
Ensembl:MGP_CAROLIEiJ_G0033390
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus caroli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
26
Annotation release Status Assembly Chr Location
101 current CAROLI_EIJ_v1.1 (GCF_900094665.1) X NC_034589.1 (123185447..123268245)

Chromosome X - NC_034589.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 35A Neighboring gene centromere protein I Neighboring gene TATA-box binding protein associated factor 7 like Neighboring gene U6 spliceosomal RNA Neighboring gene osteoclast-stimulating factor 1 pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034589.1 Chromosome X Reference CAROLI_EIJ_v1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in central nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synaptic signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dystrophin-related protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mus caroli Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CAROLI_EIJ_v1.1 Primary Assembly

Genomic

  1. NC_034589.1 Reference CAROLI_EIJ_v1.1 Primary Assembly

    Range
    123185447..123268245
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029473351.1 → XP_029329211.1  dystrophin-related protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P7QUB4
    Conserved Domains (5) summary
    cd00176
    Location:111 → 339
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:357 → 385
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:608 → 656
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    TIGR02169
    Location:716 → 882
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    cd16248
    Location:422 → 583
    EFh_DRP-2; EF-hand-like motif found in dystrophin-related protein 2 (DRP-2)

  2. XM_029473349.1 → XP_029329209.1  dystrophin-related protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P7QUB4
    Conserved Domains (5) summary
    cd00176
    Location:111 → 339
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:357 → 385
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:608 → 656
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    TIGR02169
    Location:716 → 882
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    cd16248
    Location:422 → 583
    EFh_DRP-2; EF-hand-like motif found in dystrophin-related protein 2 (DRP-2)

  3. XM_029473350.1 → XP_029329210.1  dystrophin-related protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P7QUB4
    Related
    MGP_CAROLIEiJ_P0092659, MGP_CAROLIEiJ_T0092659.1
    Conserved Domains (5) summary
    cd00176
    Location:111 → 339
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd00201
    Location:357 → 385
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd02334
    Location:608 → 656
    ZZ_dystrophin; Zinc finger, ZZ type. Zinc finger present in dystrophin and dystrobrevin. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Dystrophin attaches actin filaments to an integral membrane ...
    TIGR02169
    Location:716 → 882
    SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
    cd16248
    Location:422 → 583
    EFh_DRP-2; EF-hand-like motif found in dystrophin-related protein 2 (DRP-2)

  4. XM_029473352.1 → XP_029329212.1  dystrophin-related protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A6P7QLN0
    Related
    MGP_CAROLIEiJ_T0092664.1

RNA

  1. XR_003835710.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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