U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cd74 CD74 molecule [ Mus caroli (Ryukyu mouse) ]

Gene ID: 110284732, updated on 15-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
Cd74
Gene description
CD74 molecule
See related
Ensembl:MGP_CAROLIEiJ_G0022312
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus caroli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 18
Exon count:
9
Annotation release Status Assembly Chr Location
101 current CAROLI_EIJ_v1.1 (GCF_900094665.1) 18 NC_034587.1 (57585771..57595933)

Chromosome 18 - NC_034587.1Genomic Context describing neighboring genes Neighboring gene N-deacetylase and N-sulfotransferase 1 Neighboring gene ribosomal protein S14 Neighboring gene treacle ribosome biogenesis factor 1 Neighboring gene arylsulfatase family member I

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_034587.1 Chromosome 18 Reference CAROLI_EIJ_v1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MHC class II protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables macrophage migration inhibitory factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in T cell activation involved in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in antigen processing and presentation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of DNA damage response, signal transduction by p53 class mediator IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of macrophage cytokine production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of type 2 immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein trimerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
HLA class II histocompatibility antigen gamma chain

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Mus caroli Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CAROLI_EIJ_v1.1 Primary Assembly

Genomic

  1. NC_034587.1 Reference CAROLI_EIJ_v1.1 Primary Assembly

    Range
    57585771..57595933
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021150594.2 → XP_021006253.1  HLA class II histocompatibility antigen gamma chain isoform X1

    UniProtKB/TrEMBL
    A0A6P5NYH8
    Related
    MGP_CAROLIEiJ_P0046833, MGP_CAROLIEiJ_T0046833.1
    Conserved Domains (3) summary
    cd00191
    Location:195 → 254
    TY; Thyroglobulin type I repeats.; The N-terminal region of human thyroglobulin contains 11 type-1 repeats TY repeats are proposed to be inhibitors of cysteine proteases
    pfam08831
    Location:119 → 184
    MHCassoc_trimer; Class II MHC-associated invariant chain trimerisation domain
    pfam09307
    Location:1 → 111
    MHC2-interact; CLIP, MHC2 interacting

  2. XM_021150596.2 → XP_021006255.1  HLA class II histocompatibility antigen gamma chain isoform X2

    UniProtKB/TrEMBL
    A0A6P5NTB0
    Conserved Domains (2) summary
    pfam08831
    Location:119 → 184
    MHCassoc_trimer; Class II MHC-associated invariant chain trimerisation domain
    pfam09307
    Location:1 → 111
    MHC2-interact; CLIP, MHC2 interacting
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.