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IGF2BP2 insulin like growth factor 2 mRNA binding protein 2 [ Phascolarctos cinereus (koala) ]

Gene ID: 110221233, updated on 15-Mar-2024

Summary

Gene symbol
IGF2BP2
Gene description
insulin like growth factor 2 mRNA binding protein 2
See related
Ensembl:ENSPCIG00000023547
Gene type
protein coding
RefSeq status
MODEL
Organism
Phascolarctos cinereus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Diprotodontia; Phascolarctidae; Phascolarctos
Orthologs
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Genomic context

Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
100 current phaCin_unsw_v4.1 (GCF_002099425.1) Unplaced Scaffold NW_018344061.1 (1891229..2038905, complement)

NW_018344061.1Genomic Context describing neighboring genes Neighboring gene lipase H Neighboring gene SUMO specific peptidase 2 Neighboring gene transformer 2 beta homolog Neighboring gene uncharacterized LOC110221337

Genomic regions, transcripts, and products

Genomic Sequence:
NW_018344061 Unplaced Scaffold Reference phaCin_unsw_v4.1 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mRNA 3'-UTR binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
insulin-like growth factor 2 mRNA-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Phascolarctos cinereus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference phaCin_unsw_v4.1 Primary Assembly

Genomic

  1. NW_018344061.1 Reference phaCin_unsw_v4.1 Primary Assembly

    Range
    1891229..2038905 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021005650.1XP_020861309.1  insulin-like growth factor 2 mRNA-binding protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A6P5LYN6
    Related
    ENSPCIP00000031900.2, ENSPCIT00000039211.2
    Conserved Domains (5) summary
    cd00105
    Location:273338
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:404465
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
    cd12626
    Location:177
    RRM1_IGF2BP2; RNA recognition motif 1 in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)
    pfam00013
    Location:486549
    KH_1; KH domain
    cl17169
    Location:81156
    RRM_SF; RNA recognition motif (RRM) superfamily
  2. XM_021005649.1XP_020861308.1  insulin-like growth factor 2 mRNA-binding protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P5LVS8
    Related
    ENSPCIP00000031896.2, ENSPCIT00000039207.2
    Conserved Domains (5) summary
    cd00105
    Location:273338
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:427488
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
    cd12626
    Location:177
    RRM1_IGF2BP2; RNA recognition motif 1 in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2)
    pfam00013
    Location:509572
    KH_1; KH domain
    cl17169
    Location:81156
    RRM_SF; RNA recognition motif (RRM) superfamily
  3. XM_021005651.1XP_020861310.1  insulin-like growth factor 2 mRNA-binding protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A6P5LRW9
    Conserved Domains (4) summary
    cd00105
    Location:209274
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:363424
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...
    pfam00013
    Location:445508
    KH_1; KH domain
    cl17169
    Location:1792
    RRM_SF; RNA recognition motif (RRM) superfamily

RNA

  1. XR_002328062.1 RNA Sequence