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CGAS cyclic GMP-AMP synthase [ Phascolarctos cinereus (koala) ]

Gene ID: 110217669, updated on 15-Mar-2024

Summary

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Gene symbol
CGAS
Gene description
cyclic GMP-AMP synthase
See related
Ensembl:ENSPCIG00000017982
Gene type
protein coding
RefSeq status
MODEL
Organism
Phascolarctos cinereus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Diprotodontia; Phascolarctidae; Phascolarctos
Also known as
MB21D1
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
5
Annotation release Status Assembly Chr Location
100 current phaCin_unsw_v4.1 (GCF_002099425.1) Unplaced Scaffold NW_018344033.1 (6836140..6862150, complement)

NW_018344033.1Genomic Context describing neighboring genes Neighboring gene insulin-like growth factor 2 mRNA-binding protein 3-B Neighboring gene DEAD-box helicase 43 Neighboring gene mitochondrial tRNA translation optimization 1 Neighboring gene transfer RNA lysine (anticodon UUU) Neighboring gene eukaryotic translation elongation factor 1 alpha 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_018344033 Unplaced Scaffold Reference phaCin_unsw_v4.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 2',3'-cyclic GMP-AMP synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in activation of innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to exogenous dsRNA IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in paracrine signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of defense response to virus by host IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of type I interferon production IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in site of double-strand break IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: cyclic GMP-AMP synthase
Names
Mab-21 domain containing 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Phascolarctos cinereus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference phaCin_unsw_v4.1 Primary Assembly

Genomic

  1. NW_018344033.1 Reference phaCin_unsw_v4.1 Primary Assembly

    Range
    6836140..6862150 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021000142.1 → XP_020855801.1  LOW QUALITY PROTEIN: cyclic GMP-AMP synthase

    UniProtKB/TrEMBL
    A0A6P5LJ89
    Related
    ENSPCIP00000023755.2, ENSPCIT00000029310.2
    Conserved Domains (1) summary
    pfam03281
    Location:189 → 486
    Mab-21; Mab-21 protein
Nucleotide Protein
Heading Accession and Version

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