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NTRK1 neurotrophic receptor tyrosine kinase 1 [ Odocoileus virginianus (white-tailed deer) ]

Gene ID: 110148705, updated on 11-Apr-2024

Summary

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Gene symbol
NTRK1
Gene description
neurotrophic receptor tyrosine kinase 1
See related
EnsemblRapid:ENSOVIG00010022517
Gene type
protein coding
RefSeq status
MODEL
Organism
Odocoileus virginianus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Cervidae; Odocoileinae; Odocoileus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
100 current Ovir.te_1.0 (GCF_002102435.1) Unplaced Scaffold NW_018336399.1 (867618..902290)

NW_018336399.1Genomic Context describing neighboring genes Neighboring gene proline rich mitotic checkpoint control factor Neighboring gene SH2 domain containing 2A Neighboring gene insulin receptor related receptor Neighboring gene uncharacterized LOC110148693 Neighboring gene platelet endothelial aggregation receptor 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_018336399 Unplaced Scaffold Reference Ovir.te_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotrophin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotrophin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to nerve growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nerve growth factor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
high affinity nerve growth factor receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Odocoileus virginianus texanus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Ovir.te_1.0 Primary Assembly

Genomic

  1. NW_018336399.1 Reference Ovir.te_1.0 Primary Assembly

    Range
    867618..902290
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020910851.1 → XP_020766510.1  high affinity nerve growth factor receptor isoform X3

    UniProtKB/TrEMBL
    A0A6J0YXH2
    Related
    ENSOVIP00010032074.1, ENSOVIT00010036324.1
    Conserved Domains (6) summary
    cd04971
    Location:245 → 325
    Ig_TrKABC_d5; Fifth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    cd04972
    Location:141 → 228
    Ig_TrkABC_d4; Fourth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    cd05092
    Location:443 → 722
    PTKc_TrkA; Catalytic domain of the Protein Tyrosine Kinase, Tropomyosin Related Kinase A
    sd00031
    Location:39 → 62
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:38 → 96
    LRR_8; Leucine rich repeat
    cl15307
    Location:97 → 138
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  2. XM_020910849.1 → XP_020766508.1  high affinity nerve growth factor receptor isoform X1

    UniProtKB/TrEMBL
    A0A6J0YXH3
    Conserved Domains (6) summary
    cd04971
    Location:325 → 405
    Ig_TrKABC_d5; Fifth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    cd04972
    Location:221 → 308
    Ig_TrkABC_d4; Fourth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    cd05092
    Location:523 → 802
    PTKc_TrkA; Catalytic domain of the Protein Tyrosine Kinase, Tropomyosin Related Kinase A
    sd00031
    Location:94 → 118
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:118 → 176
    LRR_8; Leucine rich repeat
    cl15307
    Location:177 → 218
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

  3. XM_020910850.1 → XP_020766509.1  high affinity nerve growth factor receptor isoform X2

    UniProtKB/TrEMBL
    A0A6J0YY62
    Related
    ENSOVIP00010032106.1, ENSOVIT00010036358.1
    Conserved Domains (6) summary
    cd04971
    Location:299 → 379
    Ig_TrKABC_d5; Fifth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    cd04972
    Location:195 → 282
    Ig_TrkABC_d4; Fourth domain (immunoglobulin-like) of Trk receptors TrkA, TrkB and TrkC
    cd05092
    Location:503 → 782
    PTKc_TrkA; Catalytic domain of the Protein Tyrosine Kinase, Tropomyosin Related Kinase A
    sd00031
    Location:68 → 92
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:92 → 150
    LRR_8; Leucine rich repeat
    cl15307
    Location:151 → 192
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
Nucleotide Protein
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