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HSPG2 heparan sulfate proteoglycan 2 [ Pogona vitticeps (central bearded dragon) ]

Gene ID: 110073100, updated on 15-Mar-2024

Summary

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Gene symbol
HSPG2
Gene description
heparan sulfate proteoglycan 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Pogona vitticeps
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Iguania; Acrodonta; Agamidae; Amphibolurinae; Pogona
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
92
Annotation release Status Assembly Chr Location
100 current pvi1.1 (GCF_900067755.1) Unplaced Scaffold NW_018150733.1 (648883..711272, complement)

NW_018150733.1Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 48 Neighboring gene low density lipoprotein receptor class A domain containing 2 Neighboring gene proproteinase E-like Neighboring gene proproteinase E-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_018150733.1 Unplaced Scaffold Reference pvi1.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: basement membrane-specific heparan sulfate proteoglycan core protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pogona vitticeps Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference pvi1.1

Genomic

  1. NW_018150733.1 Reference pvi1.1

    Range
    648883..711272 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020781969.1 → XP_020637628.1  LOW QUALITY PROTEIN: basement membrane-specific heparan sulfate proteoglycan core protein

    UniProtKB/TrEMBL
    A0A6J0SRT8
    Conserved Domains (16) summary
    cd05743
    Location:417 → 494
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan, also known as HSPG2, and similar domains
    cd05754
    Location:1743 → 1828
    Ig_Perlecan_like; Igmmunoglobulin (Ig)-like domain found in Perlecan and similar proteins
    smart00408
    Location:2341 → 2401
    IGc2; Immunoglobulin C-2 Type
    smart00180
    Location:1583 → 1631
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00409
    Location:2239 → 2315
    IG; Immunoglobulin
    cd00054
    Location:3737 → 3766
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1533 → 1581
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3796 → 3965
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:321 → 355
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam07679
    Location:3174 → 3251
    I-set; Immunoglobulin I-set domain
    pfam00053
    Location:1245 → 1292
    Laminin_EGF; Laminin EGF domain
    pfam00008
    Location:3698 → 3729
    EGF; EGF-like domain
    pfam00052
    Location:965 → 1099
    Laminin_B; Laminin B (Domain IV)
    pfam13927
    Location:1950 → 2022
    Ig_3; Immunoglobulin domain
    cl02507
    Location:88 → 201
    SEA; SEA domain
    cl28434
    Location:2777 → 2866
    I-set; Immunoglobulin I-set domain
Nucleotide Protein
Heading Accession and Version

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