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    Kif22 kinesin family member 22 [ Mus musculus (house mouse) ]

    Gene ID: 110033, updated on 9-May-2013
    Official Symbol
    Kif22provided by MGI
    Official Full Name
    kinesin family member 22provided by MGI
    Primary source
    MGI:109233
    See related
    Ensembl:ENSMUSG00000030677
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Kid; C81217; Kif22a; AU021460
    Location :
    7 F3; 7 69.29 cM
    Sequence :
    Chromosome: 7; NC_000073.6 (127027731..127042420, complement)
    See Kif22 in Epigenomics, MapViewer

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene proline-rich transmembrane protein 2 Neighboring gene MYC-associated zinc finger protein (purine-binding transcription factor) Neighboring gene zymogen granule protein 16 Neighboring gene expressed sequence AI467606

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068.
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693.
    3. Kid-mediated chromosome compaction ensures proper nuclear envelope formation. Ohsugi M, et al. Cell, 2008 Mar 7. PMID 18329364.
    4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808.
    5. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821.

    See all (26) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. These data suggest that Kid-mediated anaphase/telophase chromosome compaction prevents formation of multinucleated cells.
      Title: Kid-mediated chromosome compaction ensures proper nuclear envelope formation.
    Submit: New GeneRIF Correction
    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Markers

    Genotypes

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    microtubule motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    focal adhesion ISO
    Inferred from Sequence Orthology
    more info
    		  
    microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    spindle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Preferred Names
    kinesin-like protein KIF22
    Names
    kinesin-like protein KIF22
    kinesin family member 22A

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145588.1 → NP_663563.1  kinesin-like protein KIF22

      Status: PROVISIONAL

      Source sequence(s)
      BC003427
      Consensus CDS
      CCDS21855.1
      UniProtKB/Swiss-Prot
      Q3V300
      Related
      ENSMUSP00000032915, ENSMUST00000032915
      Conserved Domains (3) summary
      cd01376
      Location:48 – 361
      Blast Score: 1166
      KISc_KID_like; Kinesin motor domain, KIF22/Kid-like subgroup. Members of this group might play a role in regulating chromosomal movement along microtubules in mitosis. This catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. ...
      smart00129
      Location:50 – 370
      Blast Score: 1024
      KISc; Kinesin motor, catalytic domain. ATPase.
      pfam12836
      Location:591 – 641
      Blast Score: 126
      HHH_3; Helix-hairpin-helix motif

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p1 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p1 C57BL/6J

      Range
      127027731..127042420, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000029.1 Alternate Mm_Celera

      Range
      126875858..126890654, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    genomic AAHY01066421.1 (33099..42744) None
    genomic AAHY01066422.1 None
    genomic AC122863.4 (168464..183153) None
    genomic CH466531.1 EDL17493.1 mixed
      EDL17494.1 mixed
      EDL17495.1 mixed
      EDL17496.1 mixed
      EDL17497.1 mixed
    mRNA AF013119.1 AAC39968.1
    mRNA AK044826.1 None C57BL/6J
    mRNA AK075922.1 BAE43356.1 C57BL/6J
    mRNA AK084310.1 None C57BL/6J
    mRNA AK088033.1 None NOD
    mRNA AK164052.1 None C57BL/6J
    mRNA AK197204.1 None
    mRNA AK200550.1 None
    mRNA AK205411.1 None
    mRNA BC003427.1 AAH03427.1 FVB/N
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3V300.2 GenPept UniProtKB/Swiss-Prot:Q3V300

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • Order cDNA clone
        Order cDNA clone
      • BioProjects
        BioProjects related to a gene
      • BioSystems
        BioSystems
      • CCDS
        Links from Gene to CCDS are established if a gene encodes a protein sequence that is a member of a Consensus CDS (CCDS).
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • GEO Profiles
        Related GEO
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubChem Compound
        PubChem Compounds
      • PubChem Substance
        PubChem Substances
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed (GeneRIF)
        GeneRIF -- Gene Reference Into Function Staff of the Index Section in the National Library of Medicine review the current literature. When they find articles focused on the structure and function of a gene, they write a brief summary of the impact of the paper and make the connection between the citation (PubMed) and Gene. An interface exists for interested users to submit such data as well. http://www.ncbi.nlm.nih.gov/projects/GeneRIF/GeneRIFhelp.html
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • SNP
        Related SNP records
      • SNP: GeneView
        SNPs linked from GeneView
      • SNP: Genotype
        Gene Genotype Report
      • Taxonomy
        Link to related taxonomy entry
      • UniGene
        Links are provided between Gene and UniGene when both databases calculate links to the same mRNA record (gi).
      • UniSTS
        Related UniSTS records

      Links to other resources

      General information

      Related sites

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