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prex2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 [ Labrus bergylta (ballan wrasse) ]

Gene ID: 109993538, updated on 14-Mar-2024

Summary

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Gene symbol
prex2
Gene description
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
See related
Ensembl:ENSLBEG00000015956
Gene type
protein coding
RefSeq status
MODEL
Organism
Labrus bergylta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Labriformes; Labridae; Labrus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
41
Annotation release Status Assembly Chr Location
101 current BallGen_V1 (GCF_900080235.1) Unplaced Scaffold NW_018114423.1 (1505904..1592715, complement)

NW_018114423.1Genomic Context describing neighboring genes Neighboring gene sulfatase 1 Neighboring gene chromosome unknown C8orf34 homolog Neighboring gene carboxypeptidase A6 Neighboring gene ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_018114423 Unplaced Scaffold Reference BallGen_V1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Labrus bergylta Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BallGen_V1

Genomic

  1. NW_018114423.1 Reference BallGen_V1

    Range
    1505904..1592715 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020646529.2 → XP_020502185.1  phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein

    UniProtKB/TrEMBL
    A0A3Q3FKI0, A0A3Q3FMZ7
    Related
    ENSLBEP00000020864.1, ENSLBET00000021993.1
    Conserved Domains (5) summary
    cd00160
    Location:29 → 216
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd00992
    Location:680 → 747
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04440
    Location:477 → 569
    DEP_2_P-Rex; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 2 found in P-Rex-like proteins. The P-Rex family is the guanine-nucleotide exchange factor (GEF) for the small GTPase Rac that contains an N-terminal RhoGEF domain, two DEP and PDZ domains. Rac-GEF ...
    cd01224
    Location:222 → 369
    PH_Collybistin_ASEF; Collybistin/APC-stimulated guanine nucleotide exchange factor pleckstrin homology (PH) domain
    cl02442
    Location:386 → 465
    DEP; DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is ...
Nucleotide Protein
Heading Accession and Version

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