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pik3r3b phosphoinositide-3-kinase, regulatory subunit 3b (gamma) [ Monopterus albus (swamp eel) ]

Gene ID: 109965201, updated on 14-Mar-2024

Summary

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Gene symbol
pik3r3b
Gene description
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
See related
Ensembl:ENSMALG00000018825
Gene type
protein coding
RefSeq status
MODEL
Organism
Monopterus albus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Anabantaria; Synbranchiformes; Synbranchidae; Monopterus
Also known as
pik3r3
Orthologs
human zebrafish all
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Genomic context

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See pik3r3b in Genome Data Viewer
Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
100 current M_albus_1.0 (GCF_001952655.1) Unplaced Scaffold NW_018127978.1 (123639..265757)

NW_018127978.1Genomic Context describing neighboring genes Neighboring gene interferon-induced protein with tetratricopeptide repeats 1-like Neighboring gene protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) Neighboring gene tetraspanin 1 Neighboring gene microtubule associated serine/threonine kinase 2 Neighboring gene uncharacterized LOC109965219

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_018127978.1 Unplaced Scaffold Reference M_albus_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3-kinase regulatory subunit gamma
Names
phosphoinositide-3-kinase regulatory subunit 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Monopterus albus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference M_albus_1.0 Primary Assembly

Genomic

  1. NW_018127978.1 Reference M_albus_1.0 Primary Assembly

    Range
    123639..265757
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020609032.1 → XP_020464688.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X1

    UniProtKB/TrEMBL
    A0A3Q3KDS9
    Related
    ENSMALP00000027138.1, ENSMALT00000027640.1
    Conserved Domains (5) summary
    cd09930
    Location:622 → 725
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:330 → 438
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd12925
    Location:443 → 603
    iSH2_PIK3R3; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 3, PIK3R3, also called p55gamma
    cl02570
    Location:118 → 286
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    cl17036
    Location:6 → 79
    SH3; Src Homology 3 domain superfamily

  2. XM_020609033.1 → XP_020464689.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X2

    UniProtKB/TrEMBL
    A0A3Q3KCK9
    Related
    ENSMALP00000027116.1, ENSMALT00000027618.1
    Conserved Domains (5) summary
    cd09930
    Location:585 → 688
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:293 → 401
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd12925
    Location:406 → 566
    iSH2_PIK3R3; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 3, PIK3R3, also called p55gamma
    cl02570
    Location:81 → 249
    RhoGAP; GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when bound to ...
    cl17036
    Location:2 → 42
    SH3; Src Homology 3 domain superfamily

  3. XM_020609034.1 → XP_020464690.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X3

    UniProtKB/TrEMBL
    A0A3Q3K1A6, A0A3Q3R5P5
    Related
    ENSMALP00000027164.1, ENSMALT00000027666.1
    Conserved Domains (3) summary
    cd09930
    Location:363 → 466
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:71 → 179
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd12925
    Location:184 → 344
    iSH2_PIK3R3; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 3, PIK3R3, also called p55gamma

  4. XM_020609035.1 → XP_020464691.1  phosphatidylinositol 3-kinase regulatory subunit gamma isoform X4

    UniProtKB/TrEMBL
    A0A3Q3KCS2
    Related
    ENSMALP00000027196.1, ENSMALT00000027699.1
    Conserved Domains (3) summary
    cd09930
    Location:336 → 439
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:44 → 152
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd12925
    Location:157 → 317
    iSH2_PIK3R3; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 3, PIK3R3, also called p55gamma
Nucleotide Protein
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