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Asl argininosuccinate lyase [ Mus musculus (house mouse) ]

Gene ID: 109900, updated on 30-Jun-2014
Official Symbol
Aslprovided by MGI
Official Full Name
argininosuccinate lyaseprovided by MGI
Primary source
MGI:88084
See related
Ensembl:ENSMUSG00000025533; Vega:OTTMUSG00000033763
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2510006M18Rik
Location:
5 G1.3; 5 68.37 cM
Exon count:
18
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 5 NC_000071.6 (130011495..130024546, complement)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene vitamin K epoxide reductase complex, subunit 1-like 1 Neighboring gene glucuronidase, beta Neighboring gene calcitonin gene-related peptide-receptor component protein Neighboring gene protein-tyrosine sulfotransferase 1

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
argininosuccinate lyase activity ISO
Inferred from Sequence Orthology
more info
 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
lyase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
ammonia assimilation cycle IMP
Inferred from Mutant Phenotype
more info
PubMed 
arginine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
arginine biosynthetic process via ornithine IEA
Inferred from Electronic Annotation
more info
 
argininosuccinate metabolic process ISO
Inferred from Sequence Orthology
more info
 
cellular amino acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
cellular amino acid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
internal protein amino acid acetylation ISO
Inferred from Sequence Orthology
more info
 
liver development ISO
Inferred from Sequence Orthology
more info
 
locomotory behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
post-embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
urea cycle ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cell body fiber ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
mitochondrial outer membrane ISO
Inferred from Sequence Orthology
more info
 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
perikaryon ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
argininosuccinate lyase
Names
argininosuccinate lyase
ASAL
arginosuccinase
NP_598529.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133768.4NP_598529.1  argininosuccinate lyase

    See proteins identical to NP_598529.1

    Status: PROVISIONAL

    Source sequence(s)
    BC016670
    Consensus CDS
    CCDS51655.1
    UniProtKB/Swiss-Prot
    Q91YI0
    Related
    ENSMUSP00000124274, OTTMUSP00000045917, ENSMUST00000161094, OTTMUST00000085072
    Conserved Domains (2) summary
    cd01359
    Location:27459
    Blast Score: 1759
    Argininosuccinate_lyase; Argininosuccinate lyase (argininosuccinase, ASAL)
    PLN02646
    Location:1463
    Blast Score: 1750
    PLN02646; argininosuccinate lyase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000071.6 

    Range
    130011495..130024546
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006504340.1XP_006504403.1  

    Conserved Domains (2) summary
    cd01359
    Location:76508
    Blast Score: 1769
    Argininosuccinate_lyase; Argininosuccinate lyase (argininosuccinase, ASAL)
    PLN02646
    Location:46512
    Blast Score: 1758
    PLN02646; argininosuccinate lyase
  2. XM_006504339.1XP_006504402.1  

    Conserved Domains (2) summary
    cd01359
    Location:78510
    Blast Score: 1765
    Argininosuccinate_lyase; Argininosuccinate lyase (argininosuccinase, ASAL)
    PLN02646
    Location:48514
    Blast Score: 1758
    PLN02646; argininosuccinate lyase
  3. XM_006504341.1XP_006504404.1  

    See proteins identical to XP_006504404.1

    UniProtKB/Swiss-Prot
    Q91YI0
    Related
    ENSMUSP00000123799, OTTMUSP00000045916, ENSMUST00000159619, OTTMUST00000085071
    Conserved Domains (2) summary
    cd01359
    Location:27459
    Blast Score: 1759
    Argininosuccinate_lyase; Argininosuccinate lyase (argininosuccinase, ASAL)
    PLN02646
    Location:1463
    Blast Score: 1750
    PLN02646; argininosuccinate lyase

RNA

  1. XR_377101.1 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000027.1 

    Range
    127015654..127028488
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)