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    IMMT inner membrane protein, mitochondrial [ Homo sapiens (human) ]

    Gene ID: 10989, updated on 14-May-2013
    Official Symbol
    IMMTprovided by HGNC
    Official Full Name
    inner membrane protein, mitochondrialprovided by HGNC
    Primary source
    HGNC:6047
    Locus tag
    PIG4
    See related
    Ensembl:ENSG00000132305; HPRD:02658; MIM:600378; Vega:OTTHUMG00000153170
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HMP; P87; P89; PIG4; PIG52; MINOS2; P87/89
    Location :
    2p11.2; 2
    Sequence :
    Chromosome: 2; NC_000002.11 (86371055..86422893, complement)
    See IMMT in Epigenomics, MapViewer

    Chromosome 2 - NC_000002.11Genomic Context describing neighboring genes Neighboring gene polymerase (RNA) I polypeptide A, 194kDa Neighboring gene pentatricopeptide repeat domain 3 Neighboring gene small nucleolar RNA, C/D box 94 Neighboring gene microRNA 4779 Neighboring gene mitochondrial ribosomal protein L35 Neighboring gene receptor accessory protein 1

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. Development and application of a DNA microarray-based yeast two-hybrid system. Suter B, et al. Nucleic Acids Res, 2013 Feb 1. PMID 23275563.
    2. Mitofilin regulates cytochrome c release during apoptosis by controlling mitochondrial cristae remodeling. Yang RF, et al. Biochem Biophys Res Commun, 2012 Nov 9. PMID 23058921.
    3. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. Povlsen LK, et al. Nat Cell Biol, 2012 Oct. PMID 23000965.
    4. Charting the landscape of tandem BRCT domain-mediated protein interactions. Woods NT, et al. Sci Signal, 2012 Sep 18. PMID 22990118.
    5. A census of human soluble protein complexes. Havugimana PC, et al. Cell, 2012 Aug 31. PMID 22939629.

    See all (49) citations in PubMed

    See citations in PubMed for homologs of this gene provided by HomoloGene

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. mitofilin distinctly functions in mitochondrial cristae remodeling and controls cytochrome c release during apoptosis.
      Title: Mitofilin regulates cytochrome c release during apoptosis by controlling mitochondrial cristae remodeling.
    2. CHCM1/CHCHD6, novel mitochondrial protein linked to regulation of mitofilin and mitochondrial cristae morphology.
      Title: CHCM1/CHCHD6, novel mitochondrial protein linked to regulation of mitofilin and mitochondrial cristae morphology.
    3. A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.
      Title: Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.
    4. Observational study of gene-disease association. (HuGE Navigator)
      Title: Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
    5. The mitochondrial dysfunction induced by DISC1 deficiency was partially reversed by coexpression of Mitofilin, confirming a functional link between DISC1 and Mitofilin for the normal mitochondrial function.
      Title: Disrupted-in-schizophrenia 1 (DISC1) plays essential roles in mitochondria in collaboration with Mitofilin.
    6. role in protein import related to maintenance of mitochondrial structure is suggested; mitofilin helps regulate mitochondrial morphology and four of the associated proteins (metaxins 1 and 2, SAM50 and CHCHD3) have been implicated in protein import
      Title: The mitochondrial inner membrane protein mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled-coil-helix coiled-coil-helix domain-containing protein 3 and 6 and DnaJC11.
    7. mitofilin is a critical organizer of the mitochondrial cristae morphology and thus indispensable for normal mitochondrial function
      Title: The mitochondrial inner membrane protein mitofilin controls cristae morphology.
    8. Data show that the nuclear matrix protein matrin 3, cytoskeletal motor protein HMP, and the circadian clock protein lark were significantly decreased in fetal Down syndrome brain.
      Title: Manifold decreased protein levels of matrin 3, reduced motor protein HMP and hlark in fetal Down's syndrome brain.
    Submit: New GeneRIF Correction

    Review eQTL and phenotype association data in this region using PheGenI

    Products Interactant Other Gene Complex Source Pubs Description
    NP_006830.1 DISC1    BIND  PubMed An unspecified isoform of DISC1 interacts with IMMT. 
    Q16891 Q9H8T0 AKTIP    HPRD  PubMed  
    Q16891 Q9UH62 ARMCX3    HPRD  PubMed  
    Q16891 Q9H1I8 ASCC2    HPRD  PubMed  
    Q16891 P46379 BAG6    HPRD  PubMed  
    Q16891 P35226 BMI1    HPRD  PubMed  
    Q16891 Q9H8K7 C10orf88    HPRD  PubMed  
    Q16891 Q9H0I3 CCDC113    HPRD  PubMed  
    Q16891 P48643 CCT5    HPRD  PubMed  
    Q16891 Q12873 CHD3    HPRD  PubMed  
    Q16891 P33240 CSTF2    HPRD  PubMed  
    Q16891 Signaling intermediate in Toll pathway evolutionarily conserved ECSIT    HPRD  PubMed  
    Q16891 Q9BQD7 FAM173A    HPRD  PubMed  
    Q16891 Q99689 FEZ1    HPRD  PubMed  
    Q16891 Q96AE4 FUBP1    HPRD  PubMed  
    Q16891 P54257 HAP1    HPRD  PubMed  
    Q16891 Hypothetical protein DKFZp762E1312 HJURP    HPRD  PubMed  
    Q16891 Q16891 IMMT    HPRD  PubMed  
    Q16891 O60341 KDM1A    HPRD  PubMed  
    Q16891 Q14807 KIF22    HPRD  PubMed  
    Q16891 Q5T3J3 LRIF1    HPRD  PubMed  
    Q16891 Q9H9J2 MRPL44    HPRD  PubMed  
    Q16891 Q9Y6M9 NDUFB9    HPRD  PubMed  
    Q16891 Q9UFN0 NIPSNAP3A    HPRD  PubMed  
    Q16891 O60925 PFDN1    HPRD  PubMed  
    Q16891 Q8N2W9 PIAS4    HPRD  PubMed  
    Q16891 Q8NCC3 PLA2G15    HPRD  PubMed  
    Q16891 P50336 PPOX    HPRD  PubMed  
    Q16891 P48634 PRRC2A    HPRD  PubMed  
    Q16891 O15258 RER1    HPRD  PubMed  
    Q16891 Q9NX18 SDHAF2    HPRD  PubMed  
    Q16891 O95295 SNAPIN    HPRD  PubMed  
    Q16891 Arsenite resistance protein 2 SRRT    HPRD  PubMed  
    Q16891 Q9H169 STMN4    HPRD  PubMed  
    Q16891 Q13190 STX5    HPRD  PubMed  
    Q16891 O14530 TXNDC9    HPRD  PubMed  
    Q16891 Q9NRR5 UBQLN4    HPRD  PubMed  
    BioGRID:116185 BioGRID:122157 AKTIP    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:106715 ALB    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:119614 ARMCX3    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:123921 ASCC2    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:107776 ATF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:116185 BioGRID:106997 ATP5C1    BioGRID  PubMed Co-fractionation 
    BioGRID:116185 BioGRID:112217 ATXN1    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:113647 BAG6    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:107116 BMI1    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:123064 C10orf88    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:122420 C8orf33    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:107252 CALM1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:116185 BioGRID:118843 CCDC113    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:116603 CCT5    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:116312 CDC37    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:107459 CDK9    BioGRID  PubMed Co-fractionation 
    BioGRID:116185 BioGRID:107532 CHD3    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:107612 CLN3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:116185 BioGRID:107860 CSTF2    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:118061 DISC1    BioGRID  PubMed Affinity Capture-Western; Co-localization; Far Western; Reconstituted Complex; Two-hybrid 
    BioGRID:116185 BioGRID:119446 ECSIT    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:108223 ECT2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:116185 BioGRID:108237 EEF1A1    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:114214 EIF3F    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:116185 BioGRID:108347 EP300    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:108403 ESR1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:116185 BioGRID:122439 FAM173A    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:114997 FEZ1    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:114480 HAP1    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:109343 HIVEP1    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:120635 HJURP    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:109406 HMOX2    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:115530 HNRNPR    BioGRID  PubMed Co-fractionation 
    BioGRID:116185 BioGRID:119128 HP1BP3    BioGRID  PubMed Co-fractionation 
    BioGRID:116185 BioGRID:109622 ICT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:116185 BioGRID:116185 IMMT    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:109883 ITGA4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:116185 BioGRID:116667 KDM1A    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:110033 KIF22    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:110036 KPNA2    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:120905 LRIF1    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:115014 MDC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:116185 BioGRID:136699 MINOS1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Co-fractionation 
    BioGRID:116185 BioGRID:122389 MRPL44    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:112214 MSMO1    BioGRID  PubMed Co-fractionation 
    BioGRID:116185 BioGRID:123527 NDEL1    BioGRID  PubMed Far Western; Reconstituted Complex; Two-hybrid 
    BioGRID:116185 BioGRID:110784 NDUFA9    BioGRID  PubMed Co-fractionation 
    BioGRID:116185 BioGRID:110795 NDUFB9    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:110826 NEK2    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:117432 NIPSNAP3A    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:110909 NOS3    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:106652 PARP1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:116185 BioGRID:115017 PDE4DIP    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:111223 PFDN1    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:119624 PIAS4    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:117181 PLA2G15    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:111492 PPOX    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:113646 PRRC2A    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:116262 RER1    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:120288 SDHAF2    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:116982 SIRT3    BioGRID  PubMed Positive Genetic 
    BioGRID:116185 BioGRID:119602 SIRT7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:116185 BioGRID:112490 SMN1    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:117101 SNAPIN    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:119626 SRRT    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:123515 STMN4    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:112680 STX5    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:112497 SUMO2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:116185 BioGRID:122548 TAF1D    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:112791 TCF3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:116185 BioGRID:112938 TK1    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:112992 TNNT1    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:117577 TRAF3IP1    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:115695 TUBGCP3    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:115487 TXNDC9    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:113164 UBC    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:116185 BioGRID:121223 UBQLN4    BioGRID  PubMed Two-hybrid 
    BioGRID:116185 BioGRID:113255 VCAM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:116185 BioGRID:1205541 tat    BioGRID  PubMed Affinity Capture-Western 

    Markers

    Genotypes

    Homology

    Clone Names

    • MGC111146, DKFZp779P1653

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
    		  
    mitochondrial calcium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		  
    response to cold IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    integral to membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Preferred Names
    mitochondrial inner membrane protein
    Names
    mitochondrial inner membrane protein
    mitofilin
    motor protein
    proliferation-inducing gene 4
    cell proliferation-inducing protein 52
    cell proliferation-inducing gene 4/52 protein
    mitochondrial inner membrane organizing system 2

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100169.1 → NP_001093639.1  mitochondrial inner membrane protein isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the mid-coding region, compared to variant 1, resulting in a protein (isoform 2) that is shorter than isoform 1.
      Source sequence(s)
      AY232292, BC027458, BU729109, DC403234
      Consensus CDS
      CCDS46356.1
      UniProtKB/Swiss-Prot
      Q16891
      Related
      ENSP00000407788, OTTHUMP00000225436, ENST00000442664, OTTHUMT00000376484
      Conserved Domains (1) summary
      pfam09731
      Location:319 – 745
      Blast Score: 776
      Mitofilin; Mitochondrial inner membrane protein

    2. NM_001100170.1 → NP_001093640.1  mitochondrial inner membrane protein isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice site in the mid-coding region, compared to variant 1, resulting in a protein (isoform 3) that is shorter than isoform 1.
      Source sequence(s)
      AK225780, BC002412, BC027458, BU729109, DC403234
      Consensus CDS
      CCDS46357.1
      UniProtKB/Swiss-Prot
      Q16891
      Related
      ENSP00000396899, OTTHUMP00000203280, ENST00000449247, OTTHUMT00000329911
      Conserved Domains (1) summary
      pfam09731
      Location:309 – 735
      Blast Score: 780
      Mitofilin; Mitochondrial inner membrane protein

    3. NM_006839.2 → NP_006830.2  mitochondrial inner membrane protein isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      BC002412, BC027458, BU729109, DC403234
      Consensus CDS
      CCDS46355.1
      UniProtKB/Swiss-Prot
      Q16891
      Related
      ENSP00000387262, OTTHUMP00000203278, ENST00000410111, OTTHUMT00000329909
      Conserved Domains (1) summary
      pfam09731
      Location:320 – 746
      Blast Score: 779
      Mitofilin; Mitochondrial inner membrane protein

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 104

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p10 Primary Assembly

    Genomic

    1. NC_000002.11 Reference GRCh37.p10 Primary Assembly

      Range
      86371055..86422893, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000134.1 Alternate HuRef

      Range
      86268545..86320370, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.0

    Genomic

    1. NC_018913.1 Alternate CHM1_1.0

      Range
      86235092..86286933, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    genomic ABBA01075772.1 (151683..172043) None
    genomic ABBA01075773.1 None
    genomic ABBA01075774.1 None
    genomic ABBA01075775.1 None
    genomic AC009309.4 (25101..76635) None
    genomic AMYH01010498.1 (376349..428190) None
    genomic CH471053.2 EAW99462.1
      EAW99463.1
    mRNA AF148646.1 AAF73126.1
    mRNA AK225780.1 None
    mRNA AK296676.1 BAG59273.1
    mRNA AK299014.1 BAG61094.1
    mRNA AK299596.1 BAG61528.1
    mRNA AK300017.1 BAG61832.1
    mRNA AK304197.1 BAG65077.1
    mRNA AK309004.1 None
    mRNA AK312251.1 BAG35183.1
    mRNA AY232292.1 AAP69987.1
    mRNA AY921637.1 AAX10024.1
    mRNA BC002412.2 AAH02412.1
    mRNA BC005983.1 AAH05983.1
    mRNA BC027458.1 AAH27458.1
    mRNA BC107419.1 AAI07420.1
    mRNA BU729109.1 None
    mRNA BX537369.1 CAD97612.1
    mRNA CR456793.1 CAG33074.1
    mRNA CR749590.1 CAH18389.1
    mRNA D21091.1 BAA04653.1
    mRNA D21092.1 BAA04654.1
    mRNA D21093.1 BAA04655.1
    mRNA D21094.1 BAA04656.1
    mRNA DC403234.1 None
    mRNA L42572.1 AAA85336.1
    other-genetic EU831472.1 ACE87159.1
    other-genetic EU831559.1 ACE86478.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q16891.1 GenPept UniProtKB/Swiss-Prot:Q16891

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous

      Supplemental Content

      Table of contents

      Related information

      • Order cDNA clone
        Order cDNA clone
      • BioAssay
        Related PubChem BioAssays
      • BioProjects
        BioProjects related to a gene
      • CCDS
        Links from Gene to CCDS are established if a gene encodes a protein sequence that is a member of a Consensus CDS (CCDS).
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • dbVar
        Link from Gene to dbVar
      • EST
        Link to related EST entry
      • Full text in PMC
        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • GEO Profiles
        Related GEO
      • HomoloGene
        Links between HomoloGene and Gene are provided by the HomoloGene group when a gene is included in a HomoloGene record.
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • OMIM
        Links between OMIM and Gene are calculated by Gene based on MIM numbers included in the summary and phenotype sections of the Gene record.
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubChem Compound
        PubChem Compounds
      • PubChem Substance
        PubChem Substances
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed (GeneRIF)
        GeneRIF -- Gene Reference Into Function Staff of the Index Section in the National Library of Medicine review the current literature. When they find articles focused on the structure and function of a gene, they write a brief summary of the impact of the paper and make the connection between the citation (PubMed) and Gene. An interface exists for interested users to submit such data as well. http://www.ncbi.nlm.nih.gov/projects/GeneRIF/GeneRIFhelp.html
      • PubMed (OMIM)
        Links are provided when Gene has a link to a record in OMIM, and OMIM explicitly cites these publications in PubMed.
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • SNP
        Related SNP records
      • SNP: GeneView
        SNPs linked from GeneView
      • SNP: Genotype
        Gene Genotype Report
      • Taxonomy
        Link to related taxonomy entry
      • UniGene
        Links are provided between Gene and UniGene when both databases calculate links to the same mRNA record (gi).
      • UniSTS
        Related UniSTS records

      Links to other resources

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