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lama2 laminin, alpha 2 [ Oncorhynchus kisutch (coho salmon) ]

Gene ID: 109866721, updated on 14-Mar-2024

Summary

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Gene symbol
lama2
Gene description
laminin, alpha 2
See related
Ensembl:ENSOKIG00005023645
Gene type
protein coding
RefSeq status
MODEL
Organism
Oncorhynchus kisutch
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: LG21
Exon count:
67
Annotation release Status Assembly LG Location
101 current Okis_V2 (GCF_002021735.2) LG21 NC_034194.2 (15892158..16029757)
100 previous assembly Okis_V1 (GCF_002021735.1) LG21 NC_034194.1 (13638249..13801989)

Linkage Group LG21 - NC_034194.2Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase receptor type K Neighboring gene vesicular inhibitory amino acid transporter-like Neighboring gene enoyl-[acyl-carrier-protein] reductase, mitochondrial Neighboring gene Rho GTPase activating protein 18 Neighboring gene L3MBTL histone methyl-lysine binding protein 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multi-tissue transcriptome profiles for coho salmon (Oncorhynchus kisutch), a species undergoing rediploidization following whole-genome duplication. Kim JH, et al. Mar Genomics, 2016 Feb. PMID 26614614

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables extracellular matrix structural constituent IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of embryonic development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basement membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
laminin subunit alpha-2
Names
laminin subunit alpha 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oncorhynchus kisutch Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Okis_V2 Primary Assembly

Genomic

  1. NC_034194.2 Reference Okis_V2 Primary Assembly

    Range
    15892158..16029757
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031800294.1 → XP_031656154.1  laminin subunit alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A8C7HS57
    Conserved Domains (10) summary
    smart00180
    Location:1041 → 1085
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1850 → 2202
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:1087 → 1132
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3055 → 3210
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1662 → 1918
    Laminin_I; Laminin Domain I
    pfam00054
    Location:2241 → 2381
    Laminin_G_1; Laminin G domain
    pfam00052
    Location:1307 → 1445
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:904 → 955
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:35 → 270
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06009
    Location:2104 → 2240
    Laminin_II; Laminin Domain II

  2. XM_031800298.1 → XP_031656158.1  laminin subunit alpha-2 isoform X5

    UniProtKB/TrEMBL
    A0A8C7HS57
    Conserved Domains (10) summary
    smart00180
    Location:1041 → 1085
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1850 → 2202
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:1087 → 1132
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3029 → 3184
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1662 → 1918
    Laminin_I; Laminin Domain I
    pfam00054
    Location:2241 → 2381
    Laminin_G_1; Laminin G domain
    pfam00052
    Location:1307 → 1445
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:904 → 955
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:35 → 270
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06009
    Location:2104 → 2240
    Laminin_II; Laminin Domain II

  3. XM_031800296.1 → XP_031656156.1  laminin subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A8C7HS57
    Conserved Domains (10) summary
    smart00180
    Location:1041 → 1085
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1850 → 2202
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:1087 → 1132
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3051 → 3206
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1662 → 1918
    Laminin_I; Laminin Domain I
    pfam00054
    Location:2241 → 2381
    Laminin_G_1; Laminin G domain
    pfam00052
    Location:1307 → 1445
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:904 → 955
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:35 → 270
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06009
    Location:2104 → 2240
    Laminin_II; Laminin Domain II

  4. XM_031800295.1 → XP_031656155.1  laminin subunit alpha-2 isoform X2

    UniProtKB/TrEMBL
    A0A8C7HS57
    Conserved Domains (10) summary
    smart00180
    Location:1041 → 1085
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1862 → 2200
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:1087 → 1132
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3053 → 3208
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1662 → 1918
    Laminin_I; Laminin Domain I
    pfam00054
    Location:2239 → 2379
    Laminin_G_1; Laminin G domain
    pfam00052
    Location:1307 → 1445
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:904 → 955
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:35 → 270
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06009
    Location:2104 → 2238
    Laminin_II; Laminin Domain II

  5. XM_031800297.1 → XP_031656157.1  laminin subunit alpha-2 isoform X4

    UniProtKB/TrEMBL
    A0A8C7HS57
    Conserved Domains (10) summary
    smart00180
    Location:1041 → 1085
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1862 → 2200
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:1087 → 1132
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3049 → 3204
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1662 → 1918
    Laminin_I; Laminin Domain I
    pfam00054
    Location:2239 → 2379
    Laminin_G_1; Laminin G domain
    pfam00052
    Location:1307 → 1445
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:904 → 955
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:35 → 270
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06009
    Location:2104 → 2238
    Laminin_II; Laminin Domain II

  6. XM_020455532.2 → XP_020311121.1  laminin subunit alpha-2 isoform X6

    UniProtKB/TrEMBL
    A0A8C7HS57
    Conserved Domains (10) summary
    smart00180
    Location:1041 → 1085
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1804 → 2156
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:1087 → 1132
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3009 → 3164
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1616 → 1872
    Laminin_I; Laminin Domain I
    pfam00054
    Location:2195 → 2335
    Laminin_G_1; Laminin G domain
    pfam00052
    Location:1307 → 1445
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:904 → 955
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:35 → 270
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06009
    Location:2058 → 2194
    Laminin_II; Laminin Domain II

  7. XM_031800299.1 → XP_031656159.1  laminin subunit alpha-2 isoform X7

    UniProtKB/TrEMBL
    A0A8C7HS57
    Conserved Domains (10) summary
    smart00180
    Location:1041 → 1085
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1816 → 2154
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:1087 → 1132
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3003 → 3158
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1616 → 1872
    Laminin_I; Laminin Domain I
    pfam00054
    Location:2193 → 2333
    Laminin_G_1; Laminin G domain
    pfam00052
    Location:1307 → 1445
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:904 → 955
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:35 → 270
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06009
    Location:2058 → 2192
    Laminin_II; Laminin Domain II

  8. XM_031800300.1 → XP_031656160.1  laminin subunit alpha-2 isoform X8

    UniProtKB/TrEMBL
    A0A8C7HTW9
    Conserved Domains (10) summary
    smart00180
    Location:953 → 997
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1762 → 2114
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:999 → 1044
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2967 → 3122
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1574 → 1830
    Laminin_I; Laminin Domain I
    pfam00054
    Location:2153 → 2293
    Laminin_G_1; Laminin G domain
    pfam00052
    Location:1219 → 1357
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:904 → 955
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:35 → 270
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06009
    Location:2016 → 2152
    Laminin_II; Laminin Domain II

  9. XM_031800301.1 → XP_031656161.1  laminin subunit alpha-2 isoform X9

    UniProtKB/TrEMBL
    A0A8C7HTW9
    Related
    ENSOKIP00005061725.1, ENSOKIT00005065598.1
    Conserved Domains (10) summary
    smart00180
    Location:953 → 997
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    COG1196
    Location:1762 → 2114
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00055
    Location:999 → 1044
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:2963 → 3118
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam06008
    Location:1574 → 1830
    Laminin_I; Laminin Domain I
    pfam00054
    Location:2153 → 2293
    Laminin_G_1; Laminin G domain
    pfam00052
    Location:1219 → 1357
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:904 → 955
    Laminin_EGF; Laminin EGF domain
    pfam00055
    Location:35 → 270
    Laminin_N; Laminin N-terminal (Domain VI)
    pfam06009
    Location:2016 → 2152
    Laminin_II; Laminin Domain II
Nucleotide Protein
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