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Pola1 DNA polymerase alpha 1, catalytic subunit [ Castor canadensis (American beaver) ]

Gene ID: 109703398, updated on 14-Mar-2024

Summary

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Gene symbol
Pola1
Gene description
DNA polymerase alpha 1, catalytic subunit
See related
Ensembl:ENSCCNG00000011026
Gene type
protein coding
RefSeq status
MODEL
Organism
Castor canadensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Castoridae; Castor
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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See Pola1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
36
Annotation release Status Assembly Chr Location
100 current C.can genome v1.0 (GCF_001984765.1) Unplaced Scaffold NW_017869767.1 (6119..226534, complement)

NW_017869767.1Genomic Context describing neighboring genes Neighboring gene transfer RNA threonine (anticodon AGU) Neighboring gene selenoprotein K-like Neighboring gene aristaless related homeobox

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_017869767.1 Unplaced Scaffold Reference C.can genome v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA replication origin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA-directed DNA polymerase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables purine nucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyrimidine nucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lagging strand elongation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in leading strand elongation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic DNA replication initiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of alpha DNA polymerase:primase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA polymerase alpha catalytic subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Castor canadensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference C.can genome v1.0

Genomic

  1. NW_017869767.1 Reference C.can genome v1.0

    Range
    6119..226534 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020188477.1 → XP_020044066.1  DNA polymerase alpha catalytic subunit isoform X2

    UniProtKB/TrEMBL
    A0A250Y7Q6, A0A8C0WF92
    Related
    ENSCCNP00000010562.1, ENSCCNT00000013878.1
    Conserved Domains (2) summary
    TIGR00592
    Location:56 → 1231
    pol2; DNA polymerase (pol2)
    pfam08996
    Location:1271 → 1461
    zf-DNA_Pol; DNA Polymerase alpha zinc finger

  2. XM_020188474.1 → XP_020044063.1  DNA polymerase alpha catalytic subunit isoform X1

    UniProtKB/TrEMBL
    A0A8B7WK69, A0A8C0WF92
    Conserved Domains (2) summary
    TIGR00592
    Location:56 → 1232
    pol2; DNA polymerase (pol2)
    pfam08996
    Location:1272 → 1462
    zf-DNA_Pol; DNA Polymerase alpha zinc finger
Nucleotide Protein
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