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Fasn fatty acid synthase [ Castor canadensis (American beaver) ]

Gene ID: 109702407, updated on 14-Mar-2024

Summary

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Gene symbol
Fasn
Gene description
fatty acid synthase
See related
Ensembl:ENSCCNG00000010231
Gene type
protein coding
RefSeq status
MODEL
Organism
Castor canadensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Castoridae; Castor
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
43
Annotation release Status Assembly Chr Location
100 current C.can genome v1.0 (GCF_001984765.1) Unplaced Scaffold NW_017869763.1 (531318..549547, complement)

NW_017869763.1Genomic Context describing neighboring genes Neighboring gene G protein pathway suppressor 1 Neighboring gene dihydrouridine synthase 1 like Neighboring gene coiled-coil domain containing 57 Neighboring gene solute carrier family 16 member 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_017869763.1 Unplaced Scaffold Reference C.can genome v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3-oxoacyl-[acyl-carrier-protein] synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fatty acid synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphopantetheine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fatty acid synthase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Castor canadensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference C.can genome v1.0

Genomic

  1. NW_017869763.1 Reference C.can genome v1.0

    Range
    531318..549547 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020187767.1 → XP_020043356.1  fatty acid synthase

    UniProtKB/TrEMBL
    A0A250Y8F2, A0A8B7WI96
    Conserved Domains (7) summary
    cd08954
    Location:1871 → 2107
    KR_1_FAS_SDR_x; beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 1, complex (x) SDRs
    smart00829
    Location:1559 → 1849
    PKS_ER; Enoylreductase
    COG3321
    Location:1 → 1042
    PksD; Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism]
    cd00833
    Location:2 → 404
    PKS; polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or ...
    pfam08242
    Location:1243 → 1339
    Methyltransf_12; Methyltransferase domain
    cl21494
    Location:2236 → 2483
    Abhydrolase; alpha/beta hydrolases
    cl27678
    Location:2119 → 2318
    AMP-binding; AMP-binding enzyme

  2. XM_020187760.1 → XP_020043349.1  fatty acid synthase

    UniProtKB/TrEMBL
    A0A250Y8F2, A0A8B7WI96
    Related
    ENSCCNP00000009685.1, ENSCCNT00000012761.1
    Conserved Domains (7) summary
    cd08954
    Location:1871 → 2107
    KR_1_FAS_SDR_x; beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 1, complex (x) SDRs
    smart00829
    Location:1559 → 1849
    PKS_ER; Enoylreductase
    COG3321
    Location:1 → 1042
    PksD; Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism]
    cd00833
    Location:2 → 404
    PKS; polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or ...
    pfam08242
    Location:1243 → 1339
    Methyltransf_12; Methyltransferase domain
    cl21494
    Location:2236 → 2483
    Abhydrolase; alpha/beta hydrolases
    cl27678
    Location:2119 → 2318
    AMP-binding; AMP-binding enzyme
Nucleotide Protein
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