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Clcn4 chloride voltage-gated channel 4 [ Castor canadensis (American beaver) ]

Gene ID: 109699280, updated on 14-Mar-2024

Summary

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Gene symbol
Clcn4
Gene description
chloride voltage-gated channel 4
See related
Ensembl:ENSCCNG00000020897
Gene type
protein coding
RefSeq status
MODEL
Organism
Castor canadensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Castoridae; Castor
Also known as
CLCN4-2
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
100 current C.can genome v1.0 (GCF_001984765.1) Unplaced Scaffold NW_017872496.1 (29417..68659, complement)

NW_017872496.1Genomic Context describing neighboring genes Neighboring gene TIP41-like protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_017872496.1 Unplaced Scaffold Reference C.can genome v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables voltage-gated chloride channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chloride transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in early endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synaptic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
H(+)/Cl(-) exchange transporter 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Castor canadensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference C.can genome v1.0

Genomic

  1. NW_017872496.1 Reference C.can genome v1.0

    Range
    29417..68659 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020183925.1 → XP_020039514.1  H(+)/Cl(-) exchange transporter 4 isoform X2

    UniProtKB/TrEMBL
    A0A8B7W6V3, A0A8C0X211
    Related
    ENSCCNP00000021039.1, ENSCCNT00000027117.1
    Conserved Domains (2) summary
    cd03684
    Location:78 → 557
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:581 → 718
    CBS_pair_EriC_assoc_euk_bac; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of ...

  2. XM_020183924.1 → XP_020039513.1  H(+)/Cl(-) exchange transporter 4 isoform X1

    UniProtKB/TrEMBL
    A0A8B7W6H3, A0A8C0X211
    Related
    ENSCCNP00000021047.1, ENSCCNT00000027127.1
    Conserved Domains (2) summary
    cd03684
    Location:78 → 584
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:608 → 745
    CBS_pair_EriC_assoc_euk_bac; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of ...
Nucleotide Protein
Heading Accession and Version

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