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ERBB3 erb-b2 receptor tyrosine kinase 3 [ Bos indicus (zebu cattle) ]

Gene ID: 109559378, updated on 11-Apr-2024

Summary

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Gene symbol
ERBB3
Gene description
erb-b2 receptor tyrosine kinase 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos indicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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See ERBB3 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
28
Annotation release Status Assembly Chr Location
100 current Bos_indicus_1.0 (GCF_000247795.1) 5 NC_032654.1 (61658153..61679418, complement)

Chromosome 5 - NC_032654.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC109559376 Neighboring gene zinc finger CCCH-type containing 10 Neighboring gene proliferation-associated 2G4 Neighboring gene ribosomal protein S26 Neighboring gene IKAROS family zinc finger 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_032654.1 Chromosome 5 Reference Bos_indicus_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neuregulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neuregulin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basal plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bos indicus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bos_indicus_1.0 Primary Assembly

Genomic

  1. NC_032654.1 Reference Bos_indicus_1.0 Primary Assembly

    Range
    61658153..61679418 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019961060.1 → XP_019816619.1  LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3

    UniProtKB/TrEMBL
    A0A6P5BTQ8
    Conserved Domains (5) summary
    cd12095
    Location:637 → 675
    TM_ErbB3; Transmembrane domain of ErbB3, a Protein Tyrosine Kinase
    pfam00757
    Location:182 → 329
    Furin-like; Furin-like cysteine rich region
    pfam01030
    Location:353 → 474
    Recep_L_domain; Receptor L domain
    pfam14843
    Location:499 → 629
    GF_recep_IV; Growth factor receptor domain IV
    cl21453
    Location:700 → 979
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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