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Sri sorcin [ Mus musculus (house mouse) ]

Gene ID: 109552, updated on 8-May-2016
Official Symbol
Sriprovided by MGI
Official Full Name
sorcinprovided by MGI
Primary source
MGI:MGI:98419
See related
Ensembl:ENSMUSG00000003161 Vega:OTTMUSG00000025793
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sor; 2210417O06Rik; 2900070H08Rik
Orthologs
Location:
5 A1-h; 5 3.38 cM
Exon count:
10
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 5 NC_000071.6 (8046078..8069314)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (8046080..8069245)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 30835 Neighboring gene STEAP family member 4 Neighboring gene predicted gene 15731 Neighboring gene a disintegrin and metallopeptidase domain 22 Neighboring gene predicted gene, 31032 Neighboring gene predicted gene, 21759

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calcium ion binding ISO
Inferred from Sequence Orthology
more info
 
calcium-dependent cysteine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protease binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
repressing transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
T-tubule ISO
Inferred from Sequence Orthology
more info
 
Z disc IDA
Inferred from Direct Assay
more info
PubMed 
Z disc ISO
Inferred from Sequence Orthology
more info
 
axon ISO
Inferred from Sequence Orthology
more info
 
axon terminus ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with chromaffin granule membrane ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
dendritic spine neck ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
intracellular IDA
Inferred from Direct Assay
more info
PubMed 
membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
sarcoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
smooth endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
vesicle IDA
Inferred from Direct Assay
more info
PubMed 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080974.2NP_001074443.1  sorcin isoform 1

    See identical proteins and their annotated locations for NP_001074443.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AK134747, AK168572, BQ033487
    Consensus CDS
    CCDS39009.1
    UniProtKB/Swiss-Prot
    Q6P069
    Related
    ENSMUSP00000118221, OTTMUSP00000031410, ENSMUST00000148633, OTTMUST00000063524
    Conserved Domains (3) summary
    cd00051
    Location:75130
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam13499
    Location:111163
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:112161
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
  2. NM_025618.3NP_079894.2  sorcin isoform 2

    See identical proteins and their annotated locations for NP_079894.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and the 5' coding region, compared to variant 1. It encodes isoform 2, which has a shorter and distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AK008404, AK008783, AK168572, BQ033487
    Consensus CDS
    CCDS19079.1
    UniProtKB/Swiss-Prot
    Q6P069
    Related
    ENSMUSP00000086165, OTTMUSP00000031409, ENSMUST00000088786, OTTMUST00000063523
    Conserved Domains (3) summary
    cd00051
    Location:60115
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam13499
    Location:96148
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:97146
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p3 C57BL/6J

    Range
    8046078..8069314
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006503526.2XP_006503589.1  

    Conserved Domains (3) summary
    cd00051
    Location:65120
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam13499
    Location:101153
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:102151
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
  2. XM_006503527.1XP_006503590.1  

    Conserved Domains (2) summary
    pfam13499
    Location:2678
    EF-hand_7; EF-hand domain pair
    cl08302
    Location:245
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

Alternate Mm_Celera

Genomic

  1. AC_000027.1 Alternate Mm_Celera

    Range
    7979516..8002798
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)