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magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 [ Hippocampus comes (tiger tail seahorse) ]

Gene ID: 109526771, updated on 9-Nov-2023

Summary

Gene symbol
magi2
Gene description
membrane associated guanylate kinase, WW and PDZ domain containing 2
See related
Ensembl:ENSHCOG00000011314
Gene type
protein coding
RefSeq status
MODEL
Organism
Hippocampus comes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Syngnathiaria; Syngnathiformes; Syngnathoidei; Syngnathidae; Hippocampus
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Genomic context

Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
100 current H_comes_QL1_v1 (GCF_001891065.1) Unplaced Scaffold NW_017805841.1 (1891865..2014800, complement)

NW_017805841.1Genomic Context describing neighboring genes Neighboring gene KxDL motif containing 1 Neighboring gene ERGIC and golgi 2 Neighboring gene uncharacterized LOC109526773 Neighboring gene guanine nucleotide-binding protein G(i) subunit alpha-1 Neighboring gene muscarinic acetylcholine receptor M2-like

Genomic regions, transcripts, and products

Genomic Sequence:
NW_017805841.1 Unplaced Scaffold Reference H_comes_QL1_v1 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SMAD binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables beta-1 adrenergic receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables signaling receptor complex adaptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables type II activin receptor binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in receptor clustering IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in dendrite IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Hippocampus comes Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference H_comes_QL1_v1 Primary Assembly

Genomic

  1. NW_017805841.1 Reference H_comes_QL1_v1 Primary Assembly

    Range
    1891865..2014800 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019888260.1XP_019743819.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A3Q2ZAA3
    Conserved Domains (8) summary
    smart00228
    Location:437517
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00201
    Location:313343
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd00992
    Location:9341021
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00397
    Location:358387
    WW; WW domain
    pfam09606
    Location:8681122
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam16663
    Location:199261
    MAGI_u1; Unstructured region on MAGI
    pfam16666
    Location:729785
    MAGI_u5; Unstructured region on MAGI
    cl17190
    Location:116184
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
  2. XM_019888257.1XP_019743816.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A3Q2ZAA3
    Conserved Domains (8) summary
    smart00228
    Location:437517
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00201
    Location:313343
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd00992
    Location:11901270
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00397
    Location:358387
    WW; WW domain
    pfam09606
    Location:8681122
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam16663
    Location:199261
    MAGI_u1; Unstructured region on MAGI
    pfam16666
    Location:729785
    MAGI_u5; Unstructured region on MAGI
    cl17190
    Location:116184
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
  3. XM_019888256.1XP_019743815.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2ZAA3
    Conserved Domains (8) summary
    smart00228
    Location:437517
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00201
    Location:313343
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd00992
    Location:12041284
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00397
    Location:358387
    WW; WW domain
    pfam09606
    Location:8601114
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam16663
    Location:199261
    MAGI_u1; Unstructured region on MAGI
    pfam16666
    Location:729785
    MAGI_u5; Unstructured region on MAGI
    cl17190
    Location:116184
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
  4. XM_019888255.1XP_019743814.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q2ZAA3
    Conserved Domains (8) summary
    smart00228
    Location:437517
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00201
    Location:313343
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd00992
    Location:12121292
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00397
    Location:358387
    WW; WW domain
    pfam09606
    Location:8681122
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam16663
    Location:199261
    MAGI_u1; Unstructured region on MAGI
    pfam16666
    Location:729785
    MAGI_u5; Unstructured region on MAGI
    cl17190
    Location:116184
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
  5. XM_019888261.1XP_019743820.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X6

    UniProtKB/TrEMBL
    A0A3Q2ZAA3
    Related
    ENSHCOP00000023058.1, ENSHCOT00000025611.1
    Conserved Domains (8) summary
    smart00228
    Location:437517
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00201
    Location:313343
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd00992
    Location:12041284
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00397
    Location:358387
    WW; WW domain
    pfam09606
    Location:8601114
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam16663
    Location:199261
    MAGI_u1; Unstructured region on MAGI
    pfam16666
    Location:729785
    MAGI_u5; Unstructured region on MAGI
    cl17190
    Location:116184
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
  6. XM_019888258.1XP_019743817.1  membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A3Q2ZAA3
    Conserved Domains (8) summary
    smart00228
    Location:437517
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00201
    Location:313343
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd00992
    Location:12121292
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00397
    Location:358387
    WW; WW domain
    pfam09606
    Location:8681122
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam16663
    Location:199261
    MAGI_u1; Unstructured region on MAGI
    pfam16666
    Location:729785
    MAGI_u5; Unstructured region on MAGI
    cl17190
    Location:116184
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...