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ntrk2a neurotrophic tyrosine kinase, receptor, type 2a [ Hippocampus comes (tiger tail seahorse) ]

Gene ID: 109514240, updated on 11-Apr-2024

Summary

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Gene symbol
ntrk2a
Gene description
neurotrophic tyrosine kinase, receptor, type 2a
Gene type
protein coding
RefSeq status
MODEL
Organism
Hippocampus comes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Syngnathiaria; Syngnathiformes; Syngnathoidei; Syngnathidae; Hippocampus
Also known as
ntrk2
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
100 current H_comes_QL1_v1 (GCF_001891065.1) Unplaced Scaffold NW_017805137.1 (2237328..2322624, complement)

NW_017805137.1Genomic Context describing neighboring genes Neighboring gene N-alpha-acetyltransferase 35, NatC auxiliary subunit Neighboring gene ATP/GTP binding carboxypeptidase 1 Neighboring gene solute carrier family 28 member 3 Neighboring gene RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_017805137.1 Unplaced Scaffold Reference H_comes_QL1_v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables brain-derived neurotrophic factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables brain-derived neurotrophic factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to brain-derived neurotrophic factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in trans-synaptic signaling by neuropeptide, modulating synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
BDNF/NT-3 growth factors receptor
Names
neurotrophic receptor tyrosine kinase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Hippocampus comes Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference H_comes_QL1_v1 Primary Assembly

Genomic

  1. NW_017805137.1 Reference H_comes_QL1_v1 Primary Assembly

    Range
    2237328..2322624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019867165.1 → XP_019722724.1  BDNF/NT-3 growth factors receptor isoform X3

    UniProtKB/TrEMBL
    A0A3Q2Y709
    Conserved Domains (5) summary
    sd00031
    Location:109 → 132
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:108 → 166
    LRR_8; Leucine rich repeat
    pfam13927
    Location:214 → 283
    Ig_3; Immunoglobulin domain
    cl11960
    Location:314 → 392
    Ig; Immunoglobulin domain
    cl21453
    Location:526 → 817
    PKc_like; Protein Kinases, catalytic domain

  2. XM_019867164.1 → XP_019722723.1  BDNF/NT-3 growth factors receptor isoform X2

    UniProtKB/TrEMBL
    A0A3Q2Y709
    Conserved Domains (5) summary
    sd00031
    Location:109 → 132
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:108 → 166
    LRR_8; Leucine rich repeat
    pfam13927
    Location:214 → 283
    Ig_3; Immunoglobulin domain
    cl11960
    Location:314 → 392
    Ig; Immunoglobulin domain
    cl21453
    Location:530 → 819
    PKc_like; Protein Kinases, catalytic domain

  3. XM_019867163.1 → XP_019722722.1  BDNF/NT-3 growth factors receptor isoform X1

    UniProtKB/TrEMBL
    A0A3Q2Y709
    Conserved Domains (5) summary
    sd00031
    Location:109 → 132
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:108 → 166
    LRR_8; Leucine rich repeat
    pfam13927
    Location:214 → 283
    Ig_3; Immunoglobulin domain
    cl11960
    Location:314 → 392
    Ig; Immunoglobulin domain
    cl21453
    Location:530 → 821
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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