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NSD2 nuclear receptor binding SET domain protein 2 [ Rhinolophus sinicus (Chinese rufous horseshoe bat) ]

Gene ID: 109434985, updated on 30-Mar-2024

Summary

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Gene symbol
NSD2
Gene description
nuclear receptor binding SET domain protein 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinolophus sinicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Rhinolophoidea; Rhinolophidae; Rhinolophinae; Rhinolophus
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Genomic context

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See NSD2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
100 current ASM188883v1 (GCF_001888835.1) Unplaced Scaffold NW_017739462.1 (126970..192914, complement)

NW_017739462.1Genomic Context describing neighboring genes Neighboring gene chromosome unknown C4orf48 homolog Neighboring gene negative elongation factor complex member A Neighboring gene uncharacterized LOC109434986 Neighboring gene leucine zipper and EF-hand containing transmembrane protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_017739462.1 Unplaced Scaffold Reference ASM188883v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
histone-lysine N-methyltransferase NSD2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rhinolophus sinicus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM188883v1

Genomic

  1. NW_017739462.1 Reference ASM188883v1

    Range
    126970..192914 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019712499.1 → XP_019568058.1  histone-lysine N-methyltransferase NSD2 isoform X1

    Conserved Domains (10) summary
    cd05837
    Location:221 → 340
    MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
    cd05838
    Location:907 → 1001
    WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
    smart00570
    Location:1041 → 1091
    AWS; associated with SET domains
    COG5648
    Location:444 → 603
    NHP6B; Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]
    cd00084
    Location:461 → 510
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd15651
    Location:745 → 791
    PHD2_NSD2; PHD finger 2 found in nuclear SET domain-containing protein 2 (NSD2)
    cd15654
    Location:792 → 845
    PHD3_NSD2; PHD finger 3 found in nuclear SET domain-containing protein 2 (NSD2)
    cd15657
    Location:862 → 902
    PHD4_NSD2; PHD finger 4 found in nuclear SET domain-containing protein 2 (NSD2)
    cd19211
    Location:1091 → 1232
    SET_NSD2; SET domain (including post-SET domain) found in nuclear SET domain-containing protein 2 (NSD2) and similar proteins
    cl22851
    Location:1269 → 1311
    PHD_SF; PHD finger superfamily

  2. XM_019712500.1 → XP_019568059.1  histone-lysine N-methyltransferase NSD2 isoform X1

    Conserved Domains (10) summary
    cd05837
    Location:221 → 340
    MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
    cd05838
    Location:907 → 1001
    WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
    smart00570
    Location:1041 → 1091
    AWS; associated with SET domains
    COG5648
    Location:444 → 603
    NHP6B; Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]
    cd00084
    Location:461 → 510
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd15651
    Location:745 → 791
    PHD2_NSD2; PHD finger 2 found in nuclear SET domain-containing protein 2 (NSD2)
    cd15654
    Location:792 → 845
    PHD3_NSD2; PHD finger 3 found in nuclear SET domain-containing protein 2 (NSD2)
    cd15657
    Location:862 → 902
    PHD4_NSD2; PHD finger 4 found in nuclear SET domain-containing protein 2 (NSD2)
    cd19211
    Location:1091 → 1232
    SET_NSD2; SET domain (including post-SET domain) found in nuclear SET domain-containing protein 2 (NSD2) and similar proteins
    cl22851
    Location:1269 → 1311
    PHD_SF; PHD finger superfamily

  3. XM_019712501.1 → XP_019568060.1  histone-lysine N-methyltransferase NSD2 isoform X1

    Conserved Domains (10) summary
    cd05837
    Location:221 → 340
    MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
    cd05838
    Location:907 → 1001
    WHSC1_related; The PWWP domain was first identified in the WHSC1 (Wolf-Hirschhorn syndrome candidate 1) protein, a protein implicated in Wolf-Hirschhorn syndrome (WHS). When translocated, WHSC1 plays a role in lymphoid multiple myeloma (MM) disease, also known as ...
    smart00570
    Location:1041 → 1091
    AWS; associated with SET domains
    COG5648
    Location:444 → 603
    NHP6B; Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]
    cd00084
    Location:461 → 510
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd15651
    Location:745 → 791
    PHD2_NSD2; PHD finger 2 found in nuclear SET domain-containing protein 2 (NSD2)
    cd15654
    Location:792 → 845
    PHD3_NSD2; PHD finger 3 found in nuclear SET domain-containing protein 2 (NSD2)
    cd15657
    Location:862 → 902
    PHD4_NSD2; PHD finger 4 found in nuclear SET domain-containing protein 2 (NSD2)
    cd19211
    Location:1091 → 1232
    SET_NSD2; SET domain (including post-SET domain) found in nuclear SET domain-containing protein 2 (NSD2) and similar proteins
    cl22851
    Location:1269 → 1311
    PHD_SF; PHD finger superfamily

  4. XM_019712502.1 → XP_019568061.1  histone-lysine N-methyltransferase NSD2 isoform X2

    Conserved Domains (7) summary
    cd05837
    Location:221 → 340
    MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
    PLN03237
    Location:151 → 573
    PLN03237; DNA topoisomerase 2; Provisional
    cd00084
    Location:461 → 510
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
    cd15648
    Location:698 → 740
    PHD1_NSD1_2; PHD finger 1 found in nuclear receptor-binding SET domain-containing protein NSD1 and NSD2
    cd15651
    Location:745 → 791
    PHD2_NSD2; PHD finger 2 found in nuclear SET domain-containing protein 2 (NSD2)
    cd15654
    Location:792 → 845
    PHD3_NSD2; PHD finger 3 found in nuclear SET domain-containing protein 2 (NSD2)
    cd15657
    Location:862 → 902
    PHD4_NSD2; PHD finger 4 found in nuclear SET domain-containing protein 2 (NSD2)

  5. XM_019712503.1 → XP_019568062.1  histone-lysine N-methyltransferase NSD2 isoform X3

    Conserved Domains (2) summary
    cd05837
    Location:221 → 340
    MSH6_like; The PWWP domain is present in MSH6, a mismatch repair protein homologous to bacterial MutS. The PWWP domain of histone-lysine N-methyltransferase, also known as Nuclear SET domain-containing protein 3, is also included. Mutations in MSH6 have been ...
    cd00084
    Location:461 → 510
    HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...
Nucleotide Protein
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