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BCKDK branched chain keto acid dehydrogenase kinase [ Panthera pardus (leopard) ]

Gene ID: 109259022, updated on 14-Mar-2024

Summary

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Gene symbol
BCKDK
Gene description
branched chain keto acid dehydrogenase kinase
See related
Ensembl:ENSPPRG00000008312
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera pardus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_02 current ASM2436296v1 (GCF_024362965.1) Unplaced Scaffold NW_026526980.1 (19159338..19163610, complement)
100 previous assembly PanPar1.0 (GCF_001857705.1) Unplaced Scaffold NW_017620037.1 (1165359..1169671)

NW_026526980.1Genomic Context describing neighboring genes Neighboring gene serine protease 8 Neighboring gene lysine acetyltransferase 8 Neighboring gene vitamin K epoxide reductase complex subunit 1 Neighboring gene serine protease 53 Neighboring gene zinc finger protein 668 Neighboring gene zinc finger protein 646

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables pyruvate dehydrogenase (acetyl-transferring) kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of glucose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
3-methyl-2-oxobutanoate dehydrogenase [lipoamide] kinase, mitochondrial
Names
branched chain ketoacid dehydrogenase kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_024362965.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM2436296v1 Primary Assembly

Genomic

  1. NW_026526980.1 Reference ASM2436296v1 Primary Assembly

    Range
    19159338..19163610 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019436313.2 → XP_019291858.1  3-methyl-2-oxobutanoate dehydrogenase [lipoamide] kinase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A9V1EZ22
    Conserved Domains (2) summary
    pfam10436
    Location:69 → 222
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
    cl00075
    Location:226 → 348
    HATPase; Histidine kinase-like ATPase domain

  2. XM_019436312.2 → XP_019291857.1  3-methyl-2-oxobutanoate dehydrogenase [lipoamide] kinase, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A9V1EYT4
    Related
    ENSPPRP00000015788.1
    Conserved Domains (2) summary
    cd16929
    Location:226 → 401
    HATPase_PDK-like; Histidine kinase-like ATPase domain of pyruvate dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase and related domains
    pfam10436
    Location:69 → 222
    BCDHK_Adom3; Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase
Nucleotide Protein
Heading Accession and Version

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