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nrg1 neuregulin 1 [ Scleropages formosus (Asian bonytongue) ]

Gene ID: 108929914, updated on 14-Mar-2024

Summary

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Gene symbol
nrg1
Gene description
neuregulin 1
See related
Ensembl:ENSSFOG00015006282
Gene type
protein coding
RefSeq status
MODEL
Organism
Scleropages formosus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala; Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 6
Exon count:
12
Annotation release Status Assembly Chr Location
101 current fSclFor1.1 (GCF_900964775.1) 6 NC_041811.1 (14984044..15046029, complement)
100 previous assembly ASM162426v1 (GCF_001624265.1) Unplaced Scaffold NW_017371627.1 (1095359..1153901)

Chromosome 6 - NC_041811.1Genomic Context describing neighboring genes Neighboring gene pleckstrin and Sec7 domain containing 3, like Neighboring gene fucosyltransferase 10 Neighboring gene WRN RecQ like helicase Neighboring gene purine-rich element binding protein G

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chemorepellent activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine kinase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in animal organ development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pro-neuregulin-1, membrane-bound isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Scleropages formosus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fSclFor1.1 Primary Assembly

Genomic

  1. NC_041811.1 Reference fSclFor1.1 Primary Assembly

    Range
    14984044..15046029 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029252625.1 → XP_029108458.1  pro-neuregulin-1, membrane-bound isoform isoform X6

    UniProtKB/TrEMBL
    A0A8C9RD53
    Related
    ENSSFOP00015009709.2, ENSSFOT00015009842.2
    Conserved Domains (3) summary
    PHA03099
    Location:112 → 217
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam02158
    Location:178 → 587
    Neuregulin; Neuregulin family
    cl11960
    Location:34 → 106
    Ig; Immunoglobulin domain

  2. XM_029252624.1 → XP_029108457.1  pro-neuregulin-1, membrane-bound isoform isoform X5

    UniProtKB/TrEMBL
    A0A8C9R5E7, A0A8C9R9E6
    Related
    ENSSFOP00015009679.2, ENSSFOT00015009811.2
    Conserved Domains (3) summary
    PHA02887
    Location:112 → 170
    PHA02887; EGF-like protein; Provisional
    pfam02158
    Location:181 → 590
    Neuregulin; Neuregulin family
    cl11960
    Location:34 → 106
    Ig; Immunoglobulin domain

  3. XM_029252623.1 → XP_029108456.1  pro-neuregulin-1, membrane-bound isoform isoform X4

    Conserved Domains (2) summary
    PHA02887
    Location:218 → 279
    PHA02887; EGF-like protein; Provisional
    pfam02158
    Location:287 → 695
    Neuregulin; Neuregulin family

  4. XM_029252622.1 → XP_029108455.1  pro-neuregulin-1, membrane-bound isoform isoform X3

    Conserved Domains (2) summary
    PHA03099
    Location:220 → 326
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam02158
    Location:287 → 696
    Neuregulin; Neuregulin family

  5. XM_029252621.1 → XP_029108454.1  pro-neuregulin-1, membrane-bound isoform isoform X2

    Conserved Domains (2) summary
    PHA02887
    Location:218 → 279
    PHA02887; EGF-like protein; Provisional
    pfam02158
    Location:290 → 698
    Neuregulin; Neuregulin family

  6. XM_029252620.1 → XP_029108453.1  pro-neuregulin-1, membrane-bound isoform isoform X1

    UniProtKB/TrEMBL
    A0A8C9RCM1
    Related
    ENSSFOP00015009722.2, ENSSFOT00015009858.2
    Conserved Domains (2) summary
    PHA02887
    Location:218 → 279
    PHA02887; EGF-like protein; Provisional
    pfam02158
    Location:290 → 699
    Neuregulin; Neuregulin family

  7. XM_029252626.1 → XP_029108459.1  pro-neuregulin-1, membrane-bound isoform isoform X7

    Conserved Domains (1) summary
    pfam02158
    Location:1 → 386
    Neuregulin; Neuregulin family
Nucleotide Protein
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