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pikfyve phosphoinositide kinase, FYVE finger containing [ Scleropages formosus (Asian bonytongue) ]

Gene ID: 108926494, updated on 14-Mar-2024

Summary

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Gene symbol
pikfyve
Gene description
phosphoinositide kinase, FYVE finger containing
See related
Ensembl:ENSSFOG00015021644
Gene type
protein coding
RefSeq status
MODEL
Organism
Scleropages formosus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala; Osteoglossomorpha; Osteoglossiformes; Osteoglossidae; Scleropages
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 1
Exon count:
41
Annotation release Status Assembly Chr Location
101 current fSclFor1.1 (GCF_900964775.1) 1 NC_041806.1 (27594091..27620659, complement)
100 previous assembly ASM162426v1 (GCF_001624265.1) Unplaced Scaffold NW_017371573.1 (96297..122898, complement)

Chromosome 1 - NC_041806.1Genomic Context describing neighboring genes Neighboring gene splicing factor 3b, subunit 1 Neighboring gene ankyrin repeat domain 44 Neighboring gene uncharacterized LOC108926460 Neighboring gene shugoshin 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-phosphate 5-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 3-phosphate 5-kinase
Names
phosphoinositide kinase, FYVE-type zinc finger containing

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Scleropages formosus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fSclFor1.1 Primary Assembly

Genomic

  1. NC_041806.1 Reference fSclFor1.1 Primary Assembly

    Range
    27594091..27620659 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018739202.2 → XP_018594718.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C9SE39, A0A8C9TL64
    Related
    ENSSFOP00015034004.2, ENSSFOT00015034382.2
    Conserved Domains (4) summary
    cd03334
    Location:623 → 884
    Fab1_TCP; TCP-1 like domain of the eukaryotic phosphatidylinositol 3-phosphate (PtdIns3P) 5-kinase Fab1. Fab1p is important for vacuole size regulation, presumably by modulating PtdIns(3,5)P2 effector activity. In the human homolog p235/PIKfyve deletion of this ...
    cd04448
    Location:362 → 443
    DEP_PIKfyve; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in fungal RhoGEF (GDP/GTP exchange factor) PIKfyve-like proteins. PIKfyve contains N-terminal Fyve finger and DEP domains, a central chaperonin-like domain and a C-terminal PIPK (phosphatidylinositol ...
    cd15725
    Location:159 → 220
    FYVE_PIKfyve_Fab1; FYVE domain found in metazoan PIKfyve, fungal and plant Fab1, and similar proteins
    cd17300
    Location:1775 → 2041
    PIPKc_PIKfyve; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in 1-phosphatidylinositol-3-phosphate 5-kinase and similar proteins

  2. XM_018739204.2 → XP_018594720.2  1-phosphatidylinositol 3-phosphate 5-kinase isoform X2

    UniProtKB/TrEMBL
    A0A8C9TL64
    Related
    ENSSFOP00015049786.1, ENSSFOT00015047349.1
    Conserved Domains (4) summary
    cd03334
    Location:623 → 883
    Fab1_TCP; TCP-1 like domain of the eukaryotic phosphatidylinositol 3-phosphate (PtdIns3P) 5-kinase Fab1. Fab1p is important for vacuole size regulation, presumably by modulating PtdIns(3,5)P2 effector activity. In the human homolog p235/PIKfyve deletion of this ...
    cd04448
    Location:362 → 443
    DEP_PIKfyve; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in fungal RhoGEF (GDP/GTP exchange factor) PIKfyve-like proteins. PIKfyve contains N-terminal Fyve finger and DEP domains, a central chaperonin-like domain and a C-terminal PIPK (phosphatidylinositol ...
    cd15725
    Location:159 → 220
    FYVE_PIKfyve_Fab1; FYVE domain found in metazoan PIKfyve, fungal and plant Fab1, and similar proteins
    cd17300
    Location:1774 → 2040
    PIPKc_PIKfyve; Phosphatidylinositol phosphate kinase (PIPK) catalytic domain found in 1-phosphatidylinositol-3-phosphate 5-kinase and similar proteins

  3. XM_029258161.1 → XP_029113994.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X3

    Conserved Domains (3) summary
    cd03334
    Location:623 → 884
    Fab1_TCP; TCP-1 like domain of the eukaryotic phosphatidylinositol 3-phosphate (PtdIns3P) 5-kinase Fab1. Fab1p is important for vacuole size regulation, presumably by modulating PtdIns(3,5)P2 effector activity. In the human homolog p235/PIKfyve deletion of this ...
    cd04448
    Location:362 → 443
    DEP_PIKfyve; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in fungal RhoGEF (GDP/GTP exchange factor) PIKfyve-like proteins. PIKfyve contains N-terminal Fyve finger and DEP domains, a central chaperonin-like domain and a C-terminal PIPK (phosphatidylinositol ...
    cd15725
    Location:159 → 220
    FYVE_PIKfyve_Fab1; FYVE domain found in metazoan PIKfyve, fungal and plant Fab1, and similar proteins

  4. XM_018739206.2 → XP_018594722.1  1-phosphatidylinositol 3-phosphate 5-kinase isoform X4

    UniProtKB/TrEMBL
    A0A1W4YT44
Nucleotide Protein
Heading Accession and Version

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