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SHANK2 SH3 and multiple ankyrin repeat domains 2 [ Rhinopithecus bieti (black snub-nosed monkey) ]

Gene ID: 108538860, updated on 14-Mar-2024

Summary

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Gene symbol
SHANK2
Gene description
SH3 and multiple ankyrin repeat domains 2
See related
Ensembl:ENSRBIG00000040196
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinopithecus bieti
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Rhinopithecus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
100 current ASM169854v1 (GCF_001698545.1) Unplaced Scaffold NW_016803499.1 (4003214..4670679, complement)

NW_016803499.1Genomic Context describing neighboring genes Neighboring gene histone H2A.Z pseudogene Neighboring gene PTPRF interacting protein alpha 1 Neighboring gene cortactin Neighboring gene uncharacterized LOC108538882 Neighboring gene programmed cell death protein 10 pseudogene Neighboring gene actin-85C-like Neighboring gene 7-dehydrocholesterol reductase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_016803499.1 Unplaced Scaffold Reference ASM169854v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ionotropic glutamate receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables synaptic receptor adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in dendritic spine IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SH3 and multiple ankyrin repeat domains protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rhinopithecus bieti Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM169854v1 Primary Assembly

Genomic

  1. NW_016803499.1 Reference ASM169854v1 Primary Assembly

    Range
    4003214..4670679 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017887194.1 → XP_017742683.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A2K6MAK5, A0A2K6MAM7
    Related
    ENSRBIP00000032815.1, ENSRBIT00000056792.1
    Conserved Domains (8) summary
    cd09506
    Location:1781 → 1846
    SAM_Shank1,2,3; SAM domain of Shank1,2,3 family proteins
    smart00454
    Location:1782 → 1848
    SAM; Sterile alpha motif
    cd11983
    Location:528 → 579
    SH3_Shank2; Src homology 3 domain of SH3 and multiple ankyrin repeat domains protein 2
    cd00204
    Location:225 → 351
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd00992
    Location:623 → 716
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam12796
    Location:270 → 361
    Ank_2; Ankyrin repeats (3 copies)
    pfam16511
    Location:57 → 140
    FERM_f0; N-terminal or F0 domain of Talin-head FERM
    sd00045
    Location:230 → 261
    ANK; ANK repeat [structural motif]

  2. XM_017887185.1 → XP_017742674.1  SH3 and multiple ankyrin repeat domains protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A2K6MAK2
    Related
    ENSRBIP00000032807.1, ENSRBIT00000056784.1
Nucleotide Protein
Heading Accession and Version

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