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ret ret proto-oncogene receptor tyrosine kinase [ Pygocentrus nattereri (red-bellied piranha) ]

Gene ID: 108426787, updated on 11-Apr-2024

Summary

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Gene symbol
ret
Gene description
ret proto-oncogene receptor tyrosine kinase
See related
EnsemblRapid:ENSPNAG00000015122
Gene type
protein coding
RefSeq status
MODEL
Organism
Pygocentrus nattereri
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes; Characoidei; Pygocentrus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 5
Exon count:
19
Annotation release Status Assembly Chr Location
101 current fPygNat1.pri (GCF_015220715.1) 5 NC_051215.1 (41094852..41130941)
100 previous assembly Pygocentrus_nattereri-1.0.2 (GCF_001682695.1) Unplaced Scaffold NW_016243800.1 (903334..938632)

Chromosome 5 - NC_051215.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108426754 Neighboring gene pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha Neighboring gene chondroitin sulfate N-acetylgalactosaminyltransferase 2 Neighboring gene SEC23 interacting protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
proto-oncogene tyrosine-protein kinase receptor Ret

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pygocentrus nattereri Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fPygNat1.pri

Genomic

  1. NC_051215.1 Reference fPygNat1.pri

    Range
    41094852..41130941
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037538258.1 → XP_037394155.1  proto-oncogene tyrosine-protein kinase receptor Ret isoform X2

    UniProtKB/TrEMBL
    A0A3B4CF99
    Related
    ENSPNAP00000052362.1, ENSPNAT00000072813.1
    Conserved Domains (5) summary
    cd05045
    Location:721 → 1010
    PTKc_RET; Catalytic domain of the Protein Tyrosine Kinase, REarranged during Transfection protein
    smart00112
    Location:183 → 261
    CA; Cadherin repeats
    pfam17756
    Location:26 → 146
    RET_CLD1; RET Cadherin like domain 1
    pfam17812
    Location:256 → 369
    RET_CLD3; RET Cadherin like domain 3
    pfam17813
    Location:393 → 504
    RET_CLD4; RET Cadherin like domain 4

  2. XM_017696511.2 → XP_017552000.1  proto-oncogene tyrosine-protein kinase receptor Ret isoform X1

    UniProtKB/TrEMBL
    A0A3B4CF99, A0A3B4E0B4
    Related
    ENSPNAP00000029153.1, ENSPNAT00000035372.2
Nucleotide Protein
Heading Accession and Version

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