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PLS3 plastin 3 [ Manis javanica (Malayan pangolin) ]

Gene ID: 108391664, updated on 14-Mar-2024

Summary

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Gene symbol
PLS3
Gene description
plastin 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Manis javanica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Pholidota; Manidae; Manis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
101 current YNU_ManJav_2.0 (GCF_014570535.1) Unplaced Scaffold NW_023436222.1 (147807..223910, complement)
100 previous assembly ManJav1.0 (GCF_001685135.1) Unplaced Scaffold NW_016529505.1 (105793..152715, complement)

NW_023436222.1Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase type IVA 2-like Neighboring gene tigger transposable element-derived protein 1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin filament bundle assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in actin filament network formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in actin filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in actin filament bundle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plastin-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Manis javanica Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference YNU_ManJav_2.0 Primary Assembly

Genomic

  1. NW_023436222.1 Reference YNU_ManJav_2.0 Primary Assembly

    Range
    147807..223910 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037001887.1 → XP_036857782.1  plastin-3

    Conserved Domains (5) summary
    cd00051
    Location:16 → 82
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd21292
    Location:101 → 245
    CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
    cd21328
    Location:254 → 375
    CH_PLS3_rpt2; second calponin homology (CH) domain found in plastin-3
    cd21331
    Location:377 → 510
    CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
    cd21334
    Location:519 → 630
    CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3

  2. XM_037001890.1 → XP_036857785.1  plastin-3

    Conserved Domains (5) summary
    cd00051
    Location:16 → 82
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd21292
    Location:101 → 245
    CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
    cd21328
    Location:254 → 375
    CH_PLS3_rpt2; second calponin homology (CH) domain found in plastin-3
    cd21331
    Location:377 → 510
    CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
    cd21334
    Location:519 → 630
    CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3

  3. XM_037001883.1 → XP_036857778.1  plastin-3

    Conserved Domains (5) summary
    cd00051
    Location:16 → 82
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd21292
    Location:101 → 245
    CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
    cd21328
    Location:254 → 375
    CH_PLS3_rpt2; second calponin homology (CH) domain found in plastin-3
    cd21331
    Location:377 → 510
    CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
    cd21334
    Location:519 → 630
    CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3

  4. XM_037001889.1 → XP_036857784.1  plastin-3

    Conserved Domains (5) summary
    cd00051
    Location:16 → 82
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd21292
    Location:101 → 245
    CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
    cd21328
    Location:254 → 375
    CH_PLS3_rpt2; second calponin homology (CH) domain found in plastin-3
    cd21331
    Location:377 → 510
    CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
    cd21334
    Location:519 → 630
    CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3

  5. XM_037001885.1 → XP_036857780.1  plastin-3

    Conserved Domains (5) summary
    cd00051
    Location:16 → 82
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd21292
    Location:101 → 245
    CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
    cd21328
    Location:254 → 375
    CH_PLS3_rpt2; second calponin homology (CH) domain found in plastin-3
    cd21331
    Location:377 → 510
    CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
    cd21334
    Location:519 → 630
    CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3

  6. XM_037001892.1 → XP_036857787.1  plastin-3

    Conserved Domains (5) summary
    cd00051
    Location:16 → 82
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd21292
    Location:101 → 245
    CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
    cd21328
    Location:254 → 375
    CH_PLS3_rpt2; second calponin homology (CH) domain found in plastin-3
    cd21331
    Location:377 → 510
    CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
    cd21334
    Location:519 → 630
    CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3

  7. XM_037001884.1 → XP_036857779.1  plastin-3

    Conserved Domains (5) summary
    cd00051
    Location:16 → 82
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd21292
    Location:101 → 245
    CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
    cd21328
    Location:254 → 375
    CH_PLS3_rpt2; second calponin homology (CH) domain found in plastin-3
    cd21331
    Location:377 → 510
    CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
    cd21334
    Location:519 → 630
    CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3

  8. XM_037001886.1 → XP_036857781.1  plastin-3

    Conserved Domains (5) summary
    cd00051
    Location:16 → 82
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd21292
    Location:101 → 245
    CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
    cd21328
    Location:254 → 375
    CH_PLS3_rpt2; second calponin homology (CH) domain found in plastin-3
    cd21331
    Location:377 → 510
    CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
    cd21334
    Location:519 → 630
    CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3

  9. XM_037001882.1 → XP_036857777.1  plastin-3

    Conserved Domains (5) summary
    cd00051
    Location:16 → 82
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd21292
    Location:101 → 245
    CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
    cd21328
    Location:254 → 375
    CH_PLS3_rpt2; second calponin homology (CH) domain found in plastin-3
    cd21331
    Location:377 → 510
    CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
    cd21334
    Location:519 → 630
    CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3

  10. XM_037001881.1 → XP_036857776.1  plastin-3

    Conserved Domains (5) summary
    cd00051
    Location:16 → 82
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd21292
    Location:101 → 245
    CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
    cd21328
    Location:254 → 375
    CH_PLS3_rpt2; second calponin homology (CH) domain found in plastin-3
    cd21331
    Location:377 → 510
    CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
    cd21334
    Location:519 → 630
    CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3

  11. XM_037001888.1 → XP_036857783.1  plastin-3

    Conserved Domains (5) summary
    cd00051
    Location:16 → 82
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    cd21292
    Location:101 → 245
    CH_PLS_rpt1; first calponin homology (CH) domain found in the plastin family
    cd21328
    Location:254 → 375
    CH_PLS3_rpt2; second calponin homology (CH) domain found in plastin-3
    cd21331
    Location:377 → 510
    CH_PLS3_rpt3; third calponin homology (CH) domain found in plastin-3
    cd21334
    Location:519 → 630
    CH_PLS3_rpt4; fourth calponin homology (CH) domain found in plastin-3
Nucleotide Protein
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