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ern2 endoplasmic reticulum to nucleus signaling 2 [ Ictalurus punctatus (channel catfish) ]

Gene ID: 108258664, updated on 14-Mar-2024

Summary

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Gene symbol
ern2
Gene description
endoplasmic reticulum to nucleus signaling 2
See related
Ensembl:ENSIPUG00000001249
Gene type
protein coding
RefSeq status
MODEL
Organism
Ictalurus punctatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes; Ictaluridae; Ictalurus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 26
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2023_03 current Coco_2.0 (GCF_001660625.3) 26 NC_030441.2 (433436..449529)
101 previous assembly IpCoco_1.2 (GCF_001660625.2) 26 NC_030441.1 (391146..407211)

Chromosome 26 - NC_030441.2Genomic Context describing neighboring genes Neighboring gene guanine nucleotide binding protein (G protein), gamma 13a Neighboring gene CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) Neighboring gene polo-like kinase 1 (Drosophila) Neighboring gene partner and localizer of BRCA2 Neighboring gene RASD family member 3 Neighboring gene NADH:ubiquinone oxidoreductase subunit AB1a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in IRE1-mediated unfolded protein response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of IRE1-TRAF2-ASK1 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase/endoribonuclease IRE1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_001660625.3-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Coco_2.0 Primary Assembly

Genomic

  1. NC_030441.2 Reference Coco_2.0 Primary Assembly

    Range
    433436..449529
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017457458.3 → XP_017312947.1  serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1

    UniProtKB/TrEMBL
    A0A2D0Q3S8
    Related
    ENSIPUP00000001752.1

  2. XM_017457459.3 → XP_017312948.1  serine/threonine-protein kinase/endoribonuclease IRE1 isoform X2

    UniProtKB/TrEMBL
    A0A2D0Q2J0
    Related
    ENSIPUP00000001737.1
Nucleotide Protein
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Gene LinkOut

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