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Coro2a coronin, actin binding protein 2A [ Mus musculus (house mouse) ]

Gene ID: 107684, updated on 8-May-2016
Official Symbol
Coro2aprovided by MGI
Official Full Name
coronin, actin binding protein 2Aprovided by MGI
Primary source
MGI:MGI:1345966
See related
Ensembl:ENSMUSG00000028337 Vega:OTTMUSG00000006922
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
IR10; AI563590; 9030208C03Rik
Orthologs
Location:
4; 4 B1
Exon count:
15
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 4 NC_000070.6 (46536937..46601929, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (46549809..46579312, complement)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene N-acetylneuraminic acid synthase (sialic acid synthase) Neighboring gene tripartite motif-containing 14 Neighboring gene predicted gene, 16731 Neighboring gene uncharacterized LOC105247125 Neighboring gene TBC1 domain family, member 2 Neighboring gene predicted gene, 31850 Neighboring gene predicted gene, 42281

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
actin binding ISA
Inferred from Sequence Alignment
more info
PubMed 
actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
actin cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
 
brush border IDA
Inferred from Direct Assay
more info
PubMed 
transcriptional repressor complex IBA
Inferred from Biological aspect of Ancestor
more info
 
transcriptional repressor complex ISO
Inferred from Sequence Orthology
more info
 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164804.1NP_001158276.1  coronin-2A isoform 2

    See identical proteins and their annotated locations for NP_001158276.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (2) is shorter at the N-terminus, compared to isoform 1.
    Source sequence(s)
    AK030971, AK054394, AL683884, AW912496
    Consensus CDS
    CCDS18154.1
    UniProtKB/Swiss-Prot
    Q8C0P5
    UniProtKB/TrEMBL
    B1AVH4
    Related
    ENSMUSP00000103385, OTTMUSP00000007346, ENSMUST00000107756, OTTMUST00000015988
    Conserved Domains (4) summary
    pfam08953
    Location:569
    DUF1899; Domain of unknown function (DUF1899)
    PTZ00421
    Location:10517
    PTZ00421; coronin; Provisional
    pfam08954
    Location:261397
    DUF1900; Domain of unknown function (DUF1900)
    cl02567
    Location:79308
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. NM_178893.4NP_849224.2  coronin-2A isoform 1

    See identical proteins and their annotated locations for NP_849224.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK030097, AK030971, AL683884
    Consensus CDS
    CCDS71383.1
    UniProtKB/Swiss-Prot
    Q8C0P5
    UniProtKB/TrEMBL
    B1AVH5
    Related
    ENSMUSP00000103386, OTTMUSP00000007347, ENSMUST00000107757, OTTMUST00000015989
    Conserved Domains (4) summary
    pfam08953
    Location:2488
    DUF1899; Domain of unknown function (DUF1899)
    PTZ00421
    Location:29536
    PTZ00421; coronin; Provisional
    pfam08954
    Location:280416
    DUF1900; Domain of unknown function (DUF1900)
    cl02567
    Location:98327
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p3 C57BL/6J

    Range
    46536937..46601929 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011249900.1XP_011248202.1  

    See identical proteins and their annotated locations for XP_011248202.1

    UniProtKB/Swiss-Prot
    Q8C0P5
    UniProtKB/TrEMBL
    B1AVH4
    Conserved Domains (4) summary
    pfam08953
    Location:569
    DUF1899; Domain of unknown function (DUF1899)
    PTZ00421
    Location:10517
    PTZ00421; coronin; Provisional
    pfam08954
    Location:261397
    DUF1900; Domain of unknown function (DUF1900)
    cl02567
    Location:79308
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. XM_011249899.1XP_011248201.1  

    See identical proteins and their annotated locations for XP_011248201.1

    UniProtKB/TrEMBL
    B1AVH5
    Conserved Domains (4) summary
    pfam08953
    Location:2488
    DUF1899; Domain of unknown function (DUF1899)
    PTZ00421
    Location:29536
    PTZ00421; coronin; Provisional
    pfam08954
    Location:280416
    DUF1900; Domain of unknown function (DUF1900)
    cl02567
    Location:98327
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. XM_011249901.1XP_011248203.1  

    See identical proteins and their annotated locations for XP_011248203.1

    UniProtKB/Swiss-Prot
    Q8C0P5
    UniProtKB/TrEMBL
    B1AVH4
    Related
    ENSMUSP00000030021, ENSMUST00000030021
    Conserved Domains (4) summary
    pfam08953
    Location:569
    DUF1899; Domain of unknown function (DUF1899)
    PTZ00421
    Location:10517
    PTZ00421; coronin; Provisional
    pfam08954
    Location:261397
    DUF1900; Domain of unknown function (DUF1900)
    cl02567
    Location:79308
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate Mm_Celera

Genomic

  1. AC_000026.1 Alternate Mm_Celera

    Range
    46555568..46613230 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)