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SPPL2B signal peptide peptidase like 2B [ Miniopterus natalensis ]

Gene ID: 107534605, updated on 30-Mar-2024

Summary

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Gene symbol
SPPL2B
Gene description
signal peptide peptidase like 2B
Gene type
protein coding
RefSeq status
MODEL
Organism
Miniopterus natalensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Miniopteridae; Miniopterus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
16
Annotation release Status Assembly Chr Location
100 current Mnat.v1 (GCF_001595765.1) Unplaced Scaffold NW_015504465.1 (1170399..1188421)

NW_015504465.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat and Ig domain containing 3 Neighboring gene LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated Neighboring gene transmembrane serine protease 9 Neighboring gene translocase of inner mitochondrial membrane 13

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015504465.1 Unplaced Scaffold Reference Mnat.v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic endopeptidase activity, intramembrane cleaving IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane protein proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi-associated vesicle membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasmic side of endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lumenal side of endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal peptide peptidase-like 2B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Miniopterus natalensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnat.v1

Genomic

  1. NW_015504465.1 Reference Mnat.v1

    Range
    1170399..1188421
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016209758.1 → XP_016065244.1  signal peptide peptidase-like 2B isoform X1

    Conserved Domains (2) summary
    cd02129
    Location:43 → 162
    PA_hSPPL_like; PA_hSPPL_like: Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the ...
    pfam04258
    Location:212 → 504
    Peptidase_A22B; Signal peptide peptidase

  2. XM_016209762.1 → XP_016065248.1  signal peptide peptidase-like 2B isoform X5

    Conserved Domains (2) summary
    cd02129
    Location:43 → 162
    PA_hSPPL_like; PA_hSPPL_like: Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the ...
    pfam04258
    Location:212 → 504
    Peptidase_A22B; Signal peptide peptidase

  3. XM_016209759.1 → XP_016065245.1  signal peptide peptidase-like 2B isoform X2

    Conserved Domains (2) summary
    cd02129
    Location:24 → 143
    PA_hSPPL_like; PA_hSPPL_like: Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the ...
    pfam04258
    Location:193 → 485
    Peptidase_A22B; Signal peptide peptidase

  4. XM_016209761.1 → XP_016065247.1  signal peptide peptidase-like 2B isoform X4

    Conserved Domains (2) summary
    cd02129
    Location:24 → 143
    PA_hSPPL_like; PA_hSPPL_like: Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the ...
    pfam04258
    Location:193 → 464
    Peptidase_A22B; Signal peptide peptidase

  5. XM_016209760.1 → XP_016065246.1  signal peptide peptidase-like 2B isoform X3

    Conserved Domains (2) summary
    cd02129
    Location:24 → 143
    PA_hSPPL_like; PA_hSPPL_like: Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the ...
    pfam04258
    Location:192 → 484
    Peptidase_A22B; Signal peptide peptidase

  6. XM_016209763.1 → XP_016065249.1  signal peptide peptidase-like 2B isoform X6

    Conserved Domains (2) summary
    cd02129
    Location:24 → 143
    PA_hSPPL_like; PA_hSPPL_like: Protease-associated domain containing human signal peptide peptidase-like (hSPPL)-like. This group contains various PA domain-containing proteins similar to hSPPL2a and 2b. These SPPLs are GxGD aspartic proteases. SPPL2a is sorted to the ...
    pfam04258
    Location:183 → 405
    Peptidase_A22B; Signal peptide peptidase
Nucleotide Protein
Heading Accession and Version

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