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NCF4 neutrophil cytosolic factor 4 [ Rousettus aegyptiacus (Egyptian rousette) ]

Gene ID: 107519268, updated on 30-Mar-2024

Summary

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Gene symbol
NCF4
Gene description
neutrophil cytosolic factor 4
Locus tag
HJG63_013950
Gene type
protein coding
RefSeq status
MODEL
Organism
Rousettus aegyptiacus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Rousettinae; Rousettus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
101 current mRouAeg1.p (GCF_014176215.1) Unplaced Scaffold NW_023416295.1 (169117655..169136322)
100 previous assembly Raegyp2.0 (GCF_001466805.2) Unplaced Scaffold NW_015494744.1 (2688598..2707239)

NW_023416295.1Genomic Context describing neighboring genes Neighboring gene intraflagellar transport 27 Neighboring gene parvalbumin Neighboring gene colony stimulating factor 2 receptor subunit beta Neighboring gene uncharacterized LOC118613860

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables superoxide-generating NADPH oxidase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phagocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in respiratory burst IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in superoxide anion generation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NADPH oxidase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neutrophil cytosol factor 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rousettus aegyptiacus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRouAeg1.p

Genomic

  1. NW_023416295.1 Reference mRouAeg1.p

    Range
    169117655..169136322
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036237448.1 → XP_036093341.1  neutrophil cytosol factor 4 isoform X2

    Conserved Domains (1) summary
    cd06882
    Location:19 → 141
    PX_p40phox; The phosphoinositide binding Phox Homology domain of the p40phox subunit of NADPH oxidase

  2. XM_016161773.2 → XP_016017259.2  neutrophil cytosol factor 4 isoform X1

    UniProtKB/TrEMBL
    A0A7J8JJI4
    Conserved Domains (3) summary
    cd06399
    Location:238 → 329
    PB1_P40; The PB1 domain is essential part of the p40 adaptor protein which plays an important role in activating phagocyte NADPH oxidase during phagocytosis. The PB1 domain is a modular domain mediating specific protein-protein interaction which play a role in ...
    cd06882
    Location:19 → 141
    PX_p40phox; The phosphoinositide binding Phox Homology domain of the p40phox subunit of NADPH oxidase
    cd11869
    Location:175 → 227
    SH3_p40phox; Src Homology 3 domain of the p40phox subunit of NADPH oxidase
Nucleotide Protein
Heading Accession and Version

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