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MDM2 MDM2 proto-oncogene [ Rousettus aegyptiacus (Egyptian rousette) ]

Gene ID: 107512674, updated on 30-Mar-2024

Summary

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Gene symbol
MDM2
Gene description
MDM2 proto-oncogene
Locus tag
HJG63_013139
Gene type
protein coding
RefSeq status
MODEL
Organism
Rousettus aegyptiacus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Rousettinae; Rousettus
Orthologs
human mouse all
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Genomic context

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See MDM2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
101 current mRouAeg1.p (GCF_014176215.1) Unplaced Scaffold NW_023416295.1 (117345750..117365519, complement)
100 previous assembly Raegyp2.0 (GCF_001466805.2) Unplaced Scaffold NW_015494494.1 (91987..111685, complement)

NW_023416295.1Genomic Context describing neighboring genes Neighboring gene 5S ribosomal RNA Neighboring gene carboxypeptidase M Neighboring gene eukaryotic translation initiation factor 3 subunit M-like Neighboring gene solute carrier family 35 member E3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase Mdm2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rousettus aegyptiacus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRouAeg1.p

Genomic

  1. NW_023416295.1 Reference mRouAeg1.p

    Range
    117345750..117365519 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016148463.2 → XP_016003949.1  E3 ubiquitin-protein ligase Mdm2

    UniProtKB/TrEMBL
    A0A7J8JI44
    Conserved Domains (3) summary
    cd16783
    Location:436 → 492
    mRING-HC-C2H2C4_MDM2; Modified RING finger, HC subclass (C2H2C4-type), found in E3 ubiquitin-protein ligase MDM2 and similar proteins
    cd17672
    Location:25 → 107
    MDM2; p53-binding domain found in E3 ubiquitin-protein ligase MDM2 and similar proteins
    pfam00641
    Location:299 → 328
    zf-RanBP; Zn-finger in Ran binding protein and others

  2. XM_016148462.2 → XP_016003948.1  E3 ubiquitin-protein ligase Mdm2

    UniProtKB/TrEMBL
    A0A7J8JI44
    Conserved Domains (3) summary
    cd16783
    Location:436 → 492
    mRING-HC-C2H2C4_MDM2; Modified RING finger, HC subclass (C2H2C4-type), found in E3 ubiquitin-protein ligase MDM2 and similar proteins
    cd17672
    Location:25 → 107
    MDM2; p53-binding domain found in E3 ubiquitin-protein ligase MDM2 and similar proteins
    pfam00641
    Location:299 → 328
    zf-RanBP; Zn-finger in Ran binding protein and others
Nucleotide Protein
Heading Accession and Version

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