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DCP2 decapping mRNA 2 [ Rousettus aegyptiacus (Egyptian rousette) ]

Gene ID: 107512107, updated on 30-Mar-2024

Summary

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Gene symbol
DCP2
Gene description
decapping mRNA 2
Locus tag
HJG63_003702
Gene type
protein coding
RefSeq status
MODEL
Organism
Rousettus aegyptiacus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Rousettinae; Rousettus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
101 current mRouAeg1.p (GCF_014176215.1) Unplaced Scaffold NW_023416311.1 (42678508..42725172, complement)
100 previous assembly Raegyp2.0 (GCF_001466805.2) Unplaced Scaffold NW_015492877.1 (698426..741601)

NW_023416311.1Genomic Context describing neighboring genes Neighboring gene MCC regulator of WNT signaling pathway Neighboring gene 5S ribosomal RNA Neighboring gene uncharacterized LOC118606397 Neighboring gene receptor accessory protein 5 Neighboring gene signal recognition particle 19

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in deadenylation-dependent decapping of nuclear-transcribed mRNA IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in P-body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
m7GpppN-mRNA hydrolase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rousettus aegyptiacus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRouAeg1.p

Genomic

  1. NW_023416311.1 Reference mRouAeg1.p

    Range
    42678508..42725172 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036225267.1 → XP_036081160.1  m7GpppN-mRNA hydrolase isoform X1

    UniProtKB/TrEMBL
    A0A7J8EY96
    Conserved Domains (2) summary
    cd03672
    Location:97 → 254
    Dcp2p; mRNA decapping enzyme 2 (Dcp2p), the catalytic subunit, and Dcp1p are the two components of the decapping enzyme complex. Decapping is a key step in both general and nonsense-mediated 5'->3' mRNA-decay pathways. Dcp2p contains an all-alpha helical ...
    pfam05026
    Location:12 → 93
    DCP2; Dcp2, box A domain

  2. XM_036225268.1 → XP_036081161.1  m7GpppN-mRNA hydrolase isoform X2

    UniProtKB/TrEMBL
    A0A7J8EY16, A0A7J8EY96
    Conserved Domains (2) summary
    cd03672
    Location:97 → 246
    Dcp2p; mRNA decapping enzyme 2 (Dcp2p), the catalytic subunit, and Dcp1p are the two components of the decapping enzyme complex. Decapping is a key step in both general and nonsense-mediated 5'->3' mRNA-decay pathways. Dcp2p contains an all-alpha helical ...
    pfam05026
    Location:12 → 93
    DCP2; Dcp2, box A domain

  3. XM_036225269.1 → XP_036081162.1  m7GpppN-mRNA hydrolase isoform X3

    Conserved Domains (1) summary
    cl00447
    Location:4 → 35
    Nudix_Hydrolase; Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ ...
Nucleotide Protein
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