Format

Send to:

Choose Destination

Unc5b unc-5 netrin receptor B [ Mus musculus (house mouse) ]

Gene ID: 107449, updated on 28-May-2016
Official Symbol
Unc5bprovided by MGI
Official Full Name
unc-5 netrin receptor Bprovided by MGI
Primary source
MGI:MGI:894703
See related
Ensembl:ENSMUSG00000020099
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Unc5h2; A630020F16; D10Bwg0792e; 6330415E02Rik
Orthologs
Location:
10 B4; 10 31.52 cM
Exon count:
18
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 10 NC_000076.6 (60762594..60831604, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (60225343..60294329, complement)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene cadherin 23 (otocadherin) Neighboring gene V-set immunoregulatory receptor Neighboring gene predicted gene, 17455 Neighboring gene solute carrier family 29 (nucleoside transporters), member 3 Neighboring gene predicted gene, 36750 Neighboring gene microRNA 6408 Neighboring gene predicted gene, 26947 Neighboring gene polymorphic derived intron containing

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
netrin receptor activity ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
angiogenesis IEA
Inferred from Electronic Annotation
more info
 
anterior/posterior axon guidance IMP
Inferred from Mutant Phenotype
more info
PubMed 
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
axon guidance ISO
Inferred from Sequence Orthology
more info
PubMed 
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand ISO
Inferred from Sequence Orthology
more info
 
negative regulation of neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand ISO
Inferred from Sequence Orthology
more info
 
positive regulation of phosphatidylinositol 3-kinase signaling ISO
Inferred from Sequence Orthology
more info
 
signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
membrane raft ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
netrin receptor UNC5B
Names
protein unc-5 homolog 2
protein unc-5 homolog B
unc-5 homolog 2
unc-5 homolog B
unc5 homolog 2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029770.2NP_084046.2  netrin receptor UNC5B precursor

    See identical proteins and their annotated locations for NP_084046.2

    Status: VALIDATED

    Source sequence(s)
    AK154271, AK154287, BY521726, BY529391
    Consensus CDS
    CCDS23872.1
    UniProtKB/Swiss-Prot
    Q8K1S3
    Related
    ENSMUSP00000077080, ENSMUST00000077925
    Conserved Domains (5) summary
    cd08802
    Location:858941
    Death_UNC5B; Death domain found in Uncoordinated-5B
    pfam00791
    Location:541643
    ZU5; ZU5 domain
    smart00209
    Location:249300
    TSP1; Thrombospondin type 1 repeats
    pfam07679
    Location:155243
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:157243
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p3 C57BL/6J

    Range
    60762594..60831604 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513028.2XP_006513091.1  

    See identical proteins and their annotated locations for XP_006513091.1

    UniProtKB/Swiss-Prot
    Q8K1S3
    Conserved Domains (5) summary
    cd08802
    Location:847930
    Death_UNC5B; Death domain found in Uncoordinated-5B
    pfam00791
    Location:530632
    ZU5; ZU5 domain
    smart00209
    Location:249300
    TSP1; Thrombospondin type 1 repeats
    pfam07679
    Location:155243
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:157243
    Ig; Immunoglobulin domain
  2. XM_011243261.1XP_011241563.1  

    Conserved Domains (2) summary
    cd08802
    Location:521604
    Death_UNC5B; Death domain found in Uncoordinated-5B
    pfam00791
    Location:204306
    ZU5; ZU5 domain

Alternate Mm_Celera

Genomic

  1. AC_000032.1 Alternate Mm_Celera

    Range
    61863405..61932538 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)