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ptenb phosphatase and tensin homolog B [ Nothobranchius furzeri (turquoise killifish) ]

Gene ID: 107387492, updated on 14-Mar-2024

Summary

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Gene symbol
ptenb
Gene description
phosphatase and tensin homolog B
See related
Ensembl:ENSNFUG00015008622
Gene type
protein coding
RefSeq status
MODEL
Organism
Nothobranchius furzeri
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Nothobranchiidae; Nothobranchius
Also known as
pten
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_03 current UI_Nfuz_MZM_1.0 (GCF_027789165.1) Unplaced Scaffold NW_026539926.1 (30918529..30933009)
100 previous assembly Nfu_20140520 (GCF_001465895.1) sgr12 NC_029660.1 (11731970..11746671, complement)

NW_026539926.1Genomic Context describing neighboring genes Neighboring gene multiple inositol-polyphosphate phosphatase 1b Neighboring gene ATPase family AAA domain containing 1b Neighboring gene renalase, FAD-dependent amine oxidase Neighboring gene lipase, gastric

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The transcript catalogue of the short-lived fish Nothobranchius furzeri provides insights into age-dependent changes of mRNA levels. Petzold A, et al. BMC Genomics, 2013 Mar 16. PMID 23496936, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell motility IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Names
Nfu_g_1_000822

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027789165.1-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UI_Nfuz_MZM_1.0 Primary Assembly

Genomic

  1. NW_026539926.1 Reference UI_Nfuz_MZM_1.0 Primary Assembly

    Range
    30918529..30933009
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015962487.2 → XP_015817973.1  phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

    UniProtKB/TrEMBL
    A0A1A8BAN3, A0A8C6LF36
    Related
    ENSNFUP00015018048.1
    Conserved Domains (2) summary
    cd14509
    Location:25 → 182
    PTP_PTEN; protein tyrosine phosphatase-like catalytic domain of phosphatase and tensin homolog
    pfam10409
    Location:189 → 357
    PTEN_C2; C2 domain of PTEN tumor-suppressor protein
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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