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CLCN5 chloride voltage-gated channel 5 [ Protobothrops mucrosquamatus ]

Gene ID: 107303236, updated on 14-Mar-2024

Summary

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Gene symbol
CLCN5
Gene description
chloride voltage-gated channel 5
Gene type
protein coding
RefSeq status
MODEL
Organism
Protobothrops mucrosquamatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Viperidae; Crotalinae; Protobothrops
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
101 current P.Mucros_1.0 (GCF_001527695.2) Unplaced Scaffold NW_015386391.1 (366810..374708, complement)

NW_015386391.1Genomic Context describing neighboring genes Neighboring gene diacylglycerol kinase delta Neighboring gene cyclin B3 Neighboring gene ras-related GTP-binding protein A Neighboring gene transfer RNA glutamic acid (anticodon UUC)

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015386391 Unplaced Scaffold Reference P.Mucros_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables voltage-gated chloride channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chloride transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in early endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synaptic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
H(+)/Cl(-) exchange transporter 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Protobothrops mucrosquamatus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.Mucros_1.0 Primary Assembly

Genomic

  1. NW_015386391.1 Reference P.Mucros_1.0 Primary Assembly

    Range
    366810..374708 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015832438.1 → XP_015687924.1  H(+)/Cl(-) exchange transporter 5 isoform X1

    Conserved Domains (4) summary
    COG0517
    Location:591 → 737
    CBS; CBS domain [Signal transduction mechanisms]
    cd03684
    Location:72 → 578
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:601 → 739
    CBS_pair_EriC_assoc_euk_bac; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of ...
    pfam00654
    Location:157 → 558
    Voltage_CLC; Voltage gated chloride channel

  2. XM_015832439.1 → XP_015687925.1  H(+)/Cl(-) exchange transporter 5 isoform X2

    Conserved Domains (4) summary
    COG0517
    Location:591 → 737
    CBS; CBS domain [Signal transduction mechanisms]
    cd03684
    Location:72 → 578
    ClC_3_like; ClC-3-like chloride channel proteins. This CD includes ClC-3, ClC-4, ClC-5 and ClC-Y1. ClC-3 was initially cloned from rat kidney. Expression of ClC-3 produces outwardly-rectifying Cl currents that are inhibited by protein kinase C activation. It has ...
    cd04591
    Location:601 → 739
    CBS_pair_EriC_assoc_euk_bac; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of ...
    pfam00654
    Location:157 → 558
    Voltage_CLC; Voltage gated chloride channel
Nucleotide Protein
Heading Accession and Version

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