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IDE insulin degrading enzyme [ Protobothrops mucrosquamatus ]

Gene ID: 107283394, updated on 14-Mar-2024

Summary

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Gene symbol
IDE
Gene description
insulin degrading enzyme
Gene type
protein coding
RefSeq status
MODEL
Organism
Protobothrops mucrosquamatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Viperidae; Crotalinae; Protobothrops
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
101 current P.Mucros_1.0 (GCF_001527695.2) Unplaced Scaffold NW_015386420.1 (412639..483589, complement)

NW_015386420.1Genomic Context describing neighboring genes Neighboring gene membrane associated ring-CH-type finger 5 Neighboring gene cytoplasmic polyadenylation element binding protein 3 Neighboring gene 40S ribosomal protein S29 Neighboring gene kinesin family member 11 Neighboring gene hematopoietically expressed homeobox

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015386420 Unplaced Scaffold Reference P.Mucros_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in peptide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in peroxisomal matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
insulin-degrading enzyme

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Protobothrops mucrosquamatus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.Mucros_1.0 Primary Assembly

Genomic

  1. NW_015386420.1 Reference P.Mucros_1.0 Primary Assembly

    Range
    412639..483589 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015811289.1 → XP_015666775.1  insulin-degrading enzyme

    Conserved Domains (4) summary
    COG1025
    Location:53 → 961
    Ptr; Secreted/periplasmic Zn-dependent peptidases, insulinase-like [Posttranslational modification, protein turnover, chaperones]
    pfam00675
    Location:77 → 214
    Peptidase_M16; Insulinase (Peptidase family M16)
    pfam05193
    Location:241 → 419
    Peptidase_M16_C; Peptidase M16 inactive domain
    pfam16187
    Location:425 → 706
    Peptidase_M16_M; Middle or third domain of peptidase_M16
Nucleotide Protein
Heading Accession and Version

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