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Git2 GIT ArfGAP 2 [ Marmota marmota marmota (Alpine marmot) ]

Gene ID: 107154636, updated on 3-Apr-2024

Summary

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Gene symbol
Git2
Gene description
GIT ArfGAP 2
See related
Ensembl:ENSMMMG00000024385
Gene type
protein coding
RefSeq status
MODEL
Organism
Marmota marmota marmota (sub-species: marmota)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Marmota
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
101 current marMar (GCF_001458135.2) Unplaced Scaffold NW_026000130.1 (5677971..5727777, complement)
100 previous assembly marMar2.1 (GCF_001458135.1) Unplaced Scaffold NW_015351277.1 (5677971..5727147, complement)

NW_026000130.1Genomic Context describing neighboring genes Neighboring gene von Hippel-Lindau disease tumor suppressor-like Neighboring gene trichoplein keratin filament binding Neighboring gene transfer RNA valine (anticodon CAC) Neighboring gene ankyrin repeat domain 13A Neighboring gene glutathione peroxidase 1-like Neighboring gene transfer RNA alanine (anticodon CGC)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in brain development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of ARF protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ARF GTPase-activating protein GIT2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Marmota marmota marmota Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference marMar

Genomic

  1. NW_026000130.1 Reference marMar

    Range
    5677971..5727777 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015500286.2 → XP_015355772.1  ARF GTPase-activating protein GIT2 isoform X3

    UniProtKB/TrEMBL
    A0A8C6F049
    Conserved Domains (7) summary
    cd00204
    Location:47 → 158
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam08518
    Location:204 → 232
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:561 → 675
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:75 → 167
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:352 → 401
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    sd00045
    Location:75 → 103
    ANK; ANK repeat [structural motif]
    cl02464
    Location:1 → 62
    ArfGap; Putative GTPase activating protein for Arf

  2. XM_015500285.2 → XP_015355771.1  ARF GTPase-activating protein GIT2 isoform X2

    UniProtKB/TrEMBL
    A0A8C6F049
    Conserved Domains (7) summary
    cd00204
    Location:47 → 158
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam08518
    Location:203 → 231
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:575 → 689
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:75 → 167
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:351 → 415
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    sd00045
    Location:75 → 103
    ANK; ANK repeat [structural motif]
    cl02464
    Location:1 → 62
    ArfGap; Putative GTPase activating protein for Arf

  3. XM_015500288.2 → XP_015355774.1  ARF GTPase-activating protein GIT2 isoform X5

    UniProtKB/TrEMBL
    A0A8C6AGJ3
    Related
    ENSMMMP00000028002.1
    Conserved Domains (6) summary
    cd00204
    Location:47 → 158
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam08518
    Location:204 → 232
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:526 → 640
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:75 → 167
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:75 → 103
    ANK; ANK repeat [structural motif]
    cl02464
    Location:1 → 62
    ArfGap; Putative GTPase activating protein for Arf

  4. XM_015500290.2 → XP_015355776.1  ARF GTPase-activating protein GIT2 isoform X6

    UniProtKB/TrEMBL
    A0A8C6AD01
    Related
    ENSMMMP00000028003.1
    Conserved Domains (6) summary
    cd00204
    Location:47 → 158
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam08518
    Location:204 → 232
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:496 → 610
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:75 → 167
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:75 → 103
    ANK; ANK repeat [structural motif]
    cl02464
    Location:1 → 62
    ArfGap; Putative GTPase activating protein for Arf

  5. XM_015500284.2 → XP_015355770.1  ARF GTPase-activating protein GIT2 isoform X1

    UniProtKB/TrEMBL
    A0A8C6F049
    Related
    ENSMMMP00000028001.1
    Conserved Domains (7) summary
    cd00204
    Location:47 → 158
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam08518
    Location:204 → 232
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:576 → 690
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:75 → 167
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:352 → 416
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    sd00045
    Location:75 → 103
    ANK; ANK repeat [structural motif]
    cl02464
    Location:1 → 62
    ArfGap; Putative GTPase activating protein for Arf

  6. XM_015500287.2 → XP_015355773.1  ARF GTPase-activating protein GIT2 isoform X4

    UniProtKB/TrEMBL
    A0A8C6F049
    Related
    ENSMMMP00000028005.1
    Conserved Domains (7) summary
    cd00204
    Location:47 → 158
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam08518
    Location:204 → 232
    GIT_SHD; Spa2 homology domain (SHD) of GIT
    pfam12205
    Location:546 → 660
    GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
    pfam12796
    Location:75 → 167
    Ank_2; Ankyrin repeats (3 copies)
    pfam16559
    Location:352 → 416
    GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    sd00045
    Location:75 → 103
    ANK; ANK repeat [structural motif]
    cl02464
    Location:1 → 62
    ArfGap; Putative GTPase activating protein for Arf

  7. XM_048785020.1 → XP_048640977.1  ARF GTPase-activating protein GIT2 isoform X8

  8. XM_048785019.1 → XP_048640976.1  ARF GTPase-activating protein GIT2 isoform X7

Nucleotide Protein
Heading Accession and Version

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