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MDM2 MDM2 proto-oncogene [ Gekko japonicus ]

Gene ID: 107105724, updated on 14-Mar-2024

Summary

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Gene symbol
MDM2
Gene description
MDM2 proto-oncogene
Gene type
protein coding
RefSeq status
MODEL
Organism
Gekko japonicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Gekkota; Gekkonidae; Gekkoninae; Gekko
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
100 current Gekko_japonicus_V1.1 (GCF_001447785.1) Unplaced Scaffold NW_015162474.1 (1631680..1646971, complement)

NW_015162474.1Genomic Context describing neighboring genes Neighboring gene cleavage and polyadenylation specific factor 6 Neighboring gene carboxypeptidase M Neighboring gene solute carrier family 35 member E3 Neighboring gene nucleoporin 107

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015162474.1 Unplaced Scaffold Reference Gekko_japonicus_V1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables identical protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase Mdm2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gekko japonicus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Gekko_japonicus_V1.1 Primary Assembly

Genomic

  1. NW_015162474.1 Reference Gekko_japonicus_V1.1 Primary Assembly

    Range
    1631680..1646971 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015405725.1 → XP_015261211.1  E3 ubiquitin-protein ligase Mdm2 isoform X2

    Conserved Domains (3) summary
    pfam00641
    Location:294 → 323
    zf-RanBP; Zn-finger in Ran binding protein and others
    pfam02201
    Location:35 → 108
    SWIB; SWIB/MDM2 domain
    pfam13920
    Location:420 → 469
    zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)

  2. XM_015405724.1 → XP_015261210.1  E3 ubiquitin-protein ligase Mdm2 isoform X1

    Conserved Domains (3) summary
    pfam00641
    Location:295 → 324
    zf-RanBP; Zn-finger in Ran binding protein and others
    pfam02201
    Location:35 → 108
    SWIB; SWIB/MDM2 domain
    pfam13920
    Location:421 → 470
    zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)

  3. XM_015405726.1 → XP_015261212.1  E3 ubiquitin-protein ligase Mdm2 isoform X3

    Conserved Domains (3) summary
    pfam00641
    Location:289 → 318
    zf-RanBP; Zn-finger in Ran binding protein and others
    pfam02201
    Location:29 → 102
    SWIB; SWIB/MDM2 domain
    pfam13920
    Location:415 → 464
    zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
Nucleotide Protein
Heading Accession and Version

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