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TFE3 transcription factor binding to IGHM enhancer 3 [ Acinonyx jubatus (cheetah) ]

Gene ID: 106989005, updated on 13-Mar-2024

Summary

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Gene symbol
TFE3
Gene description
transcription factor binding to IGHM enhancer 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Acinonyx jubatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Acinonychinae; Acinonyx
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_04 current VMU_Ajub_asm_v1.0 (GCF_027475565.1) X NC_069389.1 (41905873..41917263, complement)

Chromosome X - NC_069389.1Genomic Context describing neighboring genes Neighboring gene potassium voltage-gated channel subfamily D member 1 Neighboring gene GRIP1 associated protein 1 Neighboring gene coiled-coil domain containing 120 Neighboring gene PRA1 domain family member 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_069389.1 Chromosome X Reference VMU_Ajub_asm_v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in humoral immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of osteoclast differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor E3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027475565.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VMU_Ajub_asm_v1.0

Genomic

  1. NC_069389.1 Reference VMU_Ajub_asm_v1.0

    Range
    41905873..41917263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027054013.2 → XP_026909814.1  transcription factor E3 isoform X1

    UniProtKB/TrEMBL
    A0A6J1YZB5
    Conserved Domains (3) summary
    cd18928
    Location:334 → 424
    bHLHzip_TFE3; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in transcription factor E3 (TFE3) and similar proteins
    pfam11851
    Location:429 → 569
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:110 → 263
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

  2. XM_027054014.2 → XP_026909815.1  transcription factor E3 isoform X2

    UniProtKB/TrEMBL
    A0A6J1Z0J8
    Conserved Domains (3) summary
    cd18928
    Location:232 → 322
    bHLHzip_TFE3; basic Helix-Loop-Helix-zipper (bHLHzip) domain found in transcription factor E3 (TFE3) and similar proteins
    pfam11851
    Location:327 → 467
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:8 → 161
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus
Nucleotide Protein
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