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TPX2 TPX2 microtubule nucleation factor [ Acinonyx jubatus (cheetah) ]

Gene ID: 106986015, updated on 13-Mar-2024

Summary

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Gene symbol
TPX2
Gene description
TPX2 microtubule nucleation factor
Gene type
protein coding
RefSeq status
MODEL
Organism
Acinonyx jubatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Acinonychinae; Acinonyx
Orthologs
human mouse all
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Genomic context

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See TPX2 in Genome Data Viewer
Location:
chromosome: A3
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2023_04 current VMU_Ajub_asm_v1.0 (GCF_027475565.1) A3 NC_069388.1 (26352070..26413015, complement)

Chromosome A3 - NC_069388.1Genomic Context describing neighboring genes Neighboring gene forkhead box S1 Neighboring gene myosin light chain kinase 2 Neighboring gene BCL2 like 1 Neighboring gene cytochrome c oxidase subunit 4 isoform 2, mitochondrial

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_069388.1 Chromosome A3 Reference VMU_Ajub_asm_v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in activation of protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mitotic spindle organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in spindle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
targeting protein for Xklp2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027475565.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VMU_Ajub_asm_v1.0

Genomic

  1. NC_069388.1 Reference VMU_Ajub_asm_v1.0

    Range
    26352070..26413015 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_053200109.1 → XP_053056084.1  targeting protein for Xklp2 isoform X2

    UniProtKB/TrEMBL
    A0A6J2A6Y9

  2. XM_015084194.3 → XP_014939680.2  targeting protein for Xklp2 isoform X1

    UniProtKB/TrEMBL
    A0A6J0A4C0
    Conserved Domains (3) summary
    pfam06886
    Location:665 → 719
    TPX2; Targeting protein for Xklp2 (TPX2)
    pfam09041
    Location:1 → 68
    Aurora-A_bind; Aurora-A binding
    pfam12214
    Location:368 → 490
    TPX2_importin; Cell cycle regulated microtubule associated protein

  3. XM_027069808.2 → XP_026925609.1  targeting protein for Xklp2 isoform X1

    UniProtKB/TrEMBL
    A0A6J0A4C0
    Conserved Domains (3) summary
    pfam06886
    Location:665 → 719
    TPX2; Targeting protein for Xklp2 (TPX2)
    pfam09041
    Location:1 → 68
    Aurora-A_bind; Aurora-A binding
    pfam12214
    Location:368 → 490
    TPX2_importin; Cell cycle regulated microtubule associated protein

  4. XM_027069811.2 → XP_026925612.1  targeting protein for Xklp2 isoform X2

    UniProtKB/TrEMBL
    A0A6J2A6Y9
    Conserved Domains (3) summary
    pfam06886
    Location:658 → 712
    TPX2; Targeting protein for Xklp2 (TPX2)
    pfam09041
    Location:1 → 68
    Aurora-A_bind; Aurora-A binding
    pfam12214
    Location:368 → 490
    TPX2_importin; Cell cycle regulated microtubule associated protein

  5. XM_015084193.3 → XP_014939679.2  targeting protein for Xklp2 isoform X1

    UniProtKB/TrEMBL
    A0A6J0A4C0
    Conserved Domains (3) summary
    pfam06886
    Location:665 → 719
    TPX2; Targeting protein for Xklp2 (TPX2)
    pfam09041
    Location:1 → 68
    Aurora-A_bind; Aurora-A binding
    pfam12214
    Location:368 → 490
    TPX2_importin; Cell cycle regulated microtubule associated protein

  6. XM_053200108.1 → XP_053056083.1  targeting protein for Xklp2 isoform X1

    UniProtKB/TrEMBL
    A0A6J0A4C0

  7. XM_053200110.1 → XP_053056085.1  targeting protein for Xklp2 isoform X2

    UniProtKB/TrEMBL
    A0A6J2A6Y9

  8. XM_027069807.2 → XP_026925608.1  targeting protein for Xklp2 isoform X1

    UniProtKB/TrEMBL
    A0A6J0A4C0
    Conserved Domains (3) summary
    pfam06886
    Location:665 → 719
    TPX2; Targeting protein for Xklp2 (TPX2)
    pfam09041
    Location:1 → 68
    Aurora-A_bind; Aurora-A binding
    pfam12214
    Location:368 → 490
    TPX2_importin; Cell cycle regulated microtubule associated protein

  9. XM_015084196.3 → XP_014939682.2  targeting protein for Xklp2 isoform X1

    UniProtKB/TrEMBL
    A0A6J0A4C0
    Conserved Domains (3) summary
    pfam06886
    Location:665 → 719
    TPX2; Targeting protein for Xklp2 (TPX2)
    pfam09041
    Location:1 → 68
    Aurora-A_bind; Aurora-A binding
    pfam12214
    Location:368 → 490
    TPX2_importin; Cell cycle regulated microtubule associated protein

  10. XM_027069809.2 → XP_026925610.1  targeting protein for Xklp2 isoform X1

    UniProtKB/TrEMBL
    A0A6J0A4C0
    Conserved Domains (3) summary
    pfam06886
    Location:665 → 719
    TPX2; Targeting protein for Xklp2 (TPX2)
    pfam09041
    Location:1 → 68
    Aurora-A_bind; Aurora-A binding
    pfam12214
    Location:368 → 490
    TPX2_importin; Cell cycle regulated microtubule associated protein
Nucleotide Protein
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