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NFASC neurofascin [ Acinonyx jubatus (cheetah) ]

Gene ID: 106972906, updated on 13-Mar-2024

Summary

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Gene symbol
NFASC
Gene description
neurofascin
Gene type
protein coding
RefSeq status
MODEL
Organism
Acinonyx jubatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Acinonychinae; Acinonyx
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: E4
Exon count:
34
Annotation release Status Assembly Chr Location
RS_2023_04 current VMU_Ajub_asm_v1.0 (GCF_027475565.1) E4 NC_069395.1 (25629539..25810916, complement)

Chromosome E4 - NC_069395.1Genomic Context describing neighboring genes Neighboring gene RB binding protein 5, histone lysine methyltransferase complex subunit Neighboring gene transmembrane protein 81 Neighboring gene contactin 2 Neighboring gene collagen alpha-1(III) chain-like Neighboring gene uncharacterized LOC106972886 Neighboring gene leucine rich repeat neuronal 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_069395.1 Chromosome E4 Reference VMU_Ajub_asm_v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell-cell adhesion mediator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in brain development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neurofascin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027475565.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VMU_Ajub_asm_v1.0

Genomic

  1. NC_069395.1 Reference VMU_Ajub_asm_v1.0

    Range
    25629539..25810916 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027074833.2 → XP_026930634.1  neurofascin isoform X3

    UniProtKB/TrEMBL
    A0A6J2APY1
    Conserved Domains (8) summary
    cd05875
    Location:161 → 237
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:732 → 822
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:647 → 728
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:1227 → 1299
    fn3; Fibronectin type III domain
    pfam13882
    Location:1345 → 1429
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:568 → 634
    Ig; Immunoglobulin domain
    cd05731
    Location:383 → 453
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:470 → 545
    Ig; Immunoglobulin domain

  2. XM_027074839.2 → XP_026930640.1  neurofascin isoform X6

    UniProtKB/TrEMBL
    A0A6J2APY9
    Conserved Domains (8) summary
    cd05875
    Location:60 → 136
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:646 → 736
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:1141 → 1213
    fn3; Fibronectin type III domain
    pfam13882
    Location:1259 → 1343
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:467 → 533
    Ig; Immunoglobulin domain
    cd05731
    Location:282 → 352
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:369 → 444
    Ig; Immunoglobulin domain
    cl28434
    Location:546 → 627
    I-set; Immunoglobulin I-set domain

  3. XM_027074831.2 → XP_026930632.1  neurofascin isoform X1

    UniProtKB/TrEMBL
    A0A6J2AKX2
    Conserved Domains (8) summary
    cd05875
    Location:161 → 237
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:747 → 837
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:647 → 728
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:1242 → 1314
    fn3; Fibronectin type III domain
    pfam13882
    Location:1360 → 1444
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:568 → 634
    Ig; Immunoglobulin domain
    cd05731
    Location:383 → 453
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:470 → 545
    Ig; Immunoglobulin domain

  4. XM_027074832.2 → XP_026930633.1  neurofascin isoform X2

    UniProtKB/TrEMBL
    A0A6J2AML7
    Conserved Domains (8) summary
    cd05875
    Location:155 → 231
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:741 → 831
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:641 → 722
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:1236 → 1308
    fn3; Fibronectin type III domain
    pfam13882
    Location:1354 → 1438
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:562 → 628
    Ig; Immunoglobulin domain
    cd05731
    Location:377 → 447
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:464 → 539
    Ig; Immunoglobulin domain

  5. XM_027074836.2 → XP_026930637.1  neurofascin isoform X7

    UniProtKB/TrEMBL
    A0A6J2AKY0
    Conserved Domains (9) summary
    cd00063
    Location:747 → 837
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:1161 → 1233
    fn3; Fibronectin type III domain
    pfam07679
    Location:647 → 728
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:1279 → 1359
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:473 → 477
    Ig; Ig strand B [structural motif]
    cd05731
    Location:371 → 453
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains
    cd05845
    Location:246 → 336
    IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05875
    Location:143 → 237
    IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:457 → 545
    Ig; Immunoglobulin domain

  6. XM_027074837.2 → XP_026930638.1  neurofascin isoform X8

    UniProtKB/TrEMBL
    A0A6J2AMM2
    Conserved Domains (7) summary
    cd05875
    Location:161 → 237
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:747 → 837
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:647 → 728
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:1270 → 1354
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:568 → 634
    Ig; Immunoglobulin domain
    cd05731
    Location:383 → 453
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:470 → 545
    Ig; Immunoglobulin domain

  7. XM_027074834.2 → XP_026930635.1  neurofascin isoform X4

    UniProtKB/TrEMBL
    A0A6J2AQH7
    Conserved Domains (8) summary
    cd05875
    Location:161 → 237
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:730 → 820
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:1225 → 1297
    fn3; Fibronectin type III domain
    pfam13882
    Location:1343 → 1427
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:551 → 617
    Ig; Immunoglobulin domain
    cd05731
    Location:366 → 436
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:453 → 528
    Ig; Immunoglobulin domain
    cl28434
    Location:630 → 711
    I-set; Immunoglobulin I-set domain

  8. XM_027074835.2 → XP_026930636.1  neurofascin isoform X5

    UniProtKB/TrEMBL
    A0A6J2ALD9
    Conserved Domains (8) summary
    cd05875
    Location:155 → 231
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:724 → 814
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:1219 → 1291
    fn3; Fibronectin type III domain
    pfam13882
    Location:1337 → 1421
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:545 → 611
    Ig; Immunoglobulin domain
    cd05731
    Location:360 → 430
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:447 → 522
    Ig; Immunoglobulin domain
    cl28434
    Location:624 → 705
    I-set; Immunoglobulin I-set domain

  9. XM_027074845.2 → XP_026930646.1  neurofascin isoform X14

    UniProtKB/TrEMBL
    A0A6J2ALE8
    Conserved Domains (8) summary
    cd00063
    Location:726 → 816
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:641 → 722
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:1168 → 1248
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:467 → 471
    Ig; Ig strand B [structural motif]
    cd05731
    Location:365 → 447
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains
    cd05845
    Location:240 → 330
    IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05875
    Location:137 → 231
    IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:451 → 539
    Ig; Immunoglobulin domain

  10. XM_027074840.2 → XP_026930641.1  neurofascin isoform X9

    UniProtKB/TrEMBL
    A0A6J2ALE3
    Conserved Domains (8) summary
    cd05875
    Location:161 → 237
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:747 → 837
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:647 → 728
    I-set; Immunoglobulin I-set domain
    pfam00041
    Location:1135 → 1207
    fn3; Fibronectin type III domain
    pfam13882
    Location:1253 → 1337
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:568 → 634
    Ig; Immunoglobulin domain
    cd05731
    Location:383 → 453
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:470 → 545
    Ig; Immunoglobulin domain

  11. XM_027074846.2 → XP_026930647.1  neurofascin isoform X15

    UniProtKB/TrEMBL
    A0A6J2AKZ3
    Conserved Domains (8) summary
    cd00063
    Location:726 → 816
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:641 → 722
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:1163 → 1243
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:467 → 471
    Ig; Ig strand B [structural motif]
    cd05731
    Location:365 → 447
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains
    cd05845
    Location:240 → 330
    IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05875
    Location:137 → 231
    IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:451 → 539
    Ig; Immunoglobulin domain

  12. XM_027074842.2 → XP_026930643.1  neurofascin isoform X11

    UniProtKB/TrEMBL
    A0A6J2AMM6
    Conserved Domains (8) summary
    cd00063
    Location:747 → 837
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:647 → 728
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:1189 → 1269
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:473 → 477
    Ig; Ig strand B [structural motif]
    cd05731
    Location:371 → 453
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains
    cd05845
    Location:246 → 336
    IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05875
    Location:143 → 237
    IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:457 → 545
    Ig; Immunoglobulin domain

  13. XM_027074844.2 → XP_026930645.1  neurofascin isoform X13

    UniProtKB/TrEMBL
    A0A6J2AQI8
    Conserved Domains (8) summary
    cd00063
    Location:741 → 831
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:641 → 722
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:1183 → 1263
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:467 → 471
    Ig; Ig strand B [structural motif]
    cd05731
    Location:365 → 447
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains
    cd05845
    Location:240 → 330
    IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05875
    Location:137 → 231
    IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:451 → 539
    Ig; Immunoglobulin domain

  14. XM_027074843.2 → XP_026930644.1  neurofascin isoform X12

    UniProtKB/TrEMBL
    A0A6J2APZ4
    Conserved Domains (8) summary
    cd00063
    Location:747 → 837
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:647 → 728
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:1184 → 1264
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:473 → 477
    Ig; Ig strand B [structural motif]
    cd05731
    Location:371 → 453
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains
    cd05845
    Location:246 → 336
    IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05875
    Location:143 → 237
    IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:457 → 545
    Ig; Immunoglobulin domain

  15. XM_027074847.2 → XP_026930648.1  neurofascin isoform X16

    UniProtKB/TrEMBL
    A0A6J2AMN1
    Conserved Domains (8) summary
    cd00063
    Location:709 → 799
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:624 → 705
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:1151 → 1231
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:450 → 454
    Ig; Ig strand B [structural motif]
    cd05731
    Location:348 → 430
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains
    cd05845
    Location:240 → 330
    IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05875
    Location:137 → 231
    IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:434 → 522
    Ig; Immunoglobulin domain

  16. XM_027074841.2 → XP_026930642.1  neurofascin isoform X10

    UniProtKB/TrEMBL
    A0A6J2AKY6
    Conserved Domains (8) summary
    cd05875
    Location:161 → 237
    Ig_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF)
    cd00063
    Location:730 → 820
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:1118 → 1190
    fn3; Fibronectin type III domain
    pfam13882
    Location:1236 → 1320
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:551 → 617
    Ig; Immunoglobulin domain
    cd05731
    Location:366 → 436
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM)
    cl11960
    Location:453 → 528
    Ig; Immunoglobulin domain
    cl28434
    Location:630 → 711
    I-set; Immunoglobulin I-set domain

  17. XM_027074848.2 → XP_026930649.1  neurofascin isoform X18

    UniProtKB/TrEMBL
    A0A6J2APZ9
    Conserved Domains (8) summary
    cd00063
    Location:726 → 816
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:641 → 722
    I-set; Immunoglobulin I-set domain
    pfam13882
    Location:1056 → 1136
    Bravo_FIGEY; Bravo-like intracellular region
    cd00096
    Location:467 → 471
    Ig; Ig strand B [structural motif]
    cd05731
    Location:365 → 447
    Ig3_L1-CAM_like; Third immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains
    cd05845
    Location:240 → 330
    IgI_2_L1-CAM_like; Second immunoglobulin (Ig)-like domain of the L1 cell adhesion molecule (CAM), and similar domains; member of the I-set of Ig superfamily (IgSF) domains
    cd05875
    Location:137 → 231
    IgI_hNeurofascin_like; Immunoglobulin (Ig)-like domain of human neurofascin (NF); member of the I-set of Ig superfamily (IgSF) domains
    cl11960
    Location:451 → 539
    Ig; Immunoglobulin domain

  18. XM_053209858.1 → XP_053065833.1  neurofascin isoform X17

Nucleotide Protein
Heading Accession and Version

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