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PLEKHG4 pleckstrin homology and RhoGEF domain containing G4 [ Acinonyx jubatus (cheetah) ]

Gene ID: 106971554, updated on 3-Apr-2024

Summary

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Gene symbol
PLEKHG4
Gene description
pleckstrin homology and RhoGEF domain containing G4
Gene type
protein coding
RefSeq status
MODEL
Organism
Acinonyx jubatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Acinonychinae; Acinonyx
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: E2
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2023_04 current VMU_Ajub_asm_v1.0 (GCF_027475565.1) E2 NC_069396.1 (18841290..18882017, complement)

Chromosome E2 - NC_069396.1Genomic Context describing neighboring genes Neighboring gene tubulin polymerization promoting protein family member 3 Neighboring gene leucine rich repeat containing 36 Neighboring gene potassium channel tetramerization domain containing 19 Neighboring gene solute carrier family 9 member A5 Neighboring gene formin homology 2 domain containing 1 Neighboring gene transmembrane protein 208

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_069396.1 Chromosome E2 Reference VMU_Ajub_asm_v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
puratrophin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027475565.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VMU_Ajub_asm_v1.0

Genomic

  1. NC_069396.1 Reference VMU_Ajub_asm_v1.0

    Range
    18841290..18882017 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_053211023.1 → XP_053066998.1  puratrophin-1 isoform X3

  2. XM_053211025.1 → XP_053067000.1  puratrophin-1 isoform X5

    UniProtKB/TrEMBL
    A0A6J2AP11

  3. XM_027075933.2 → XP_026931734.1  puratrophin-1 isoform X1

    UniProtKB/TrEMBL
    A0A6J2APG8, A0A6J2AT66
    Conserved Domains (4) summary
    cd13242
    Location:1023 → 1158
    PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
    pfam00621
    Location:860 → 1030
    RhoGEF; RhoGEF domain
    cl15787
    Location:308 → 404
    SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
    cl25732
    Location:542 → 679
    SMC_N; RecF/RecN/SMC N terminal domain

  4. XM_053211026.1 → XP_053067001.1  puratrophin-1 isoform X6

  5. XM_053211024.1 → XP_053066999.1  puratrophin-1 isoform X4

  6. XM_053211027.1 → XP_053067002.1  puratrophin-1 isoform X7

  7. XM_027075934.2 → XP_026931735.1  puratrophin-1 isoform X2

    UniProtKB/TrEMBL
    A0A6J2APG8, A0A6J2ATN4
    Conserved Domains (4) summary
    cd13242
    Location:1023 → 1158
    PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
    pfam00621
    Location:860 → 1030
    RhoGEF; RhoGEF domain
    cl15787
    Location:308 → 404
    SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...
    cl25732
    Location:542 → 679
    SMC_N; RecF/RecN/SMC N terminal domain
Nucleotide Protein
Heading Accession and Version

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