U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

HNF4A hepatocyte nuclear factor 4 alpha [ Acinonyx jubatus (cheetah) ]

Gene ID: 106968950, updated on 13-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
HNF4A
Gene description
hepatocyte nuclear factor 4 alpha
Gene type
protein coding
RefSeq status
MODEL
Organism
Acinonyx jubatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Acinonychinae; Acinonyx
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: A3
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_04 current VMU_Ajub_asm_v1.0 (GCF_027475565.1) A3 NC_069388.1 (15772653..15831558, complement)

Chromosome A3 - NC_069388.1Genomic Context describing neighboring genes Neighboring gene serine incorporator 3 Neighboring gene alpha tocopherol transfer protein like Neighboring gene uncharacterized LOC106968951 Neighboring gene R3H domain containing like Neighboring gene fat storage inducing transmembrane protein 2

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_069388.1 Chromosome A3 Reference VMU_Ajub_asm_v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear steroid receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anatomical structure development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
hepatocyte nuclear factor 4-alpha

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_027475565.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VMU_Ajub_asm_v1.0

Genomic

  1. NC_069388.1 Reference VMU_Ajub_asm_v1.0

    Range
    15772653..15831558 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_053199918.1 → XP_053055893.1  hepatocyte nuclear factor 4-alpha isoform X5

  2. XM_027070166.2 → XP_026925967.1  hepatocyte nuclear factor 4-alpha isoform X6

    UniProtKB/TrEMBL
    A0A6J2A7Y0
    Conserved Domains (2) summary
    cd06931
    Location:126 → 348
    NR_LBD_HNF4_like; The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes
    cd06960
    Location:35 → 110
    NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers

  3. XM_027070164.2 → XP_026925965.1  hepatocyte nuclear factor 4-alpha isoform X3

    UniProtKB/TrEMBL
    A0A6J2AC67
    Conserved Domains (2) summary
    cd06931
    Location:151 → 373
    NR_LBD_HNF4_like; The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes
    cd06960
    Location:60 → 135
    NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers

  4. XM_027070162.2 → XP_026925963.1  hepatocyte nuclear factor 4-alpha isoform X1

    UniProtKB/TrEMBL
    A0A6J2A8V8
    Conserved Domains (2) summary
    cd06931
    Location:151 → 373
    NR_LBD_HNF4_like; The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes
    cd06960
    Location:60 → 135
    NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers

  5. XM_027070165.2 → XP_026925966.1  hepatocyte nuclear factor 4-alpha isoform X4

    UniProtKB/TrEMBL
    A0A6J2A805
    Conserved Domains (2) summary
    cd06931
    Location:151 → 373
    NR_LBD_HNF4_like; The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes
    cd06960
    Location:60 → 135
    NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers

  6. XM_027070163.2 → XP_026925964.1  hepatocyte nuclear factor 4-alpha isoform X2

    UniProtKB/TrEMBL
    A0A6J2ABR2
    Conserved Domains (2) summary
    cd06931
    Location:151 → 373
    NR_LBD_HNF4_like; The ligand binding domain of heptocyte nuclear factor 4, which is explosively expanded in nematodes
    cd06960
    Location:60 → 135
    NR_DBD_HNF4A; DNA-binding domain of heptocyte nuclear factor 4 (HNF4) is composed of two C4-type zinc fingers
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.