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TRAF5 TNF receptor associated factor 5 [ Acinonyx jubatus (cheetah) ]

Gene ID: 106966776, updated on 13-Mar-2024

Summary

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Gene symbol
TRAF5
Gene description
TNF receptor associated factor 5
Gene type
protein coding
RefSeq status
MODEL
Organism
Acinonyx jubatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Acinonychinae; Acinonyx
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: E4
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_04 current VMU_Ajub_asm_v1.0 (GCF_027475565.1) E4 NC_069395.1 (36863348..36914693)

Chromosome E4 - NC_069395.1Genomic Context describing neighboring genes Neighboring gene ribosome biogenesis protein NSA2 homolog Neighboring gene REST corepressor 3 Neighboring gene vesicle transport protein GOT1B-like Neighboring gene RD3 regulator of GUCY2D Neighboring gene solute carrier family 30 member 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_069395.1 Chromosome E4 Reference VMU_Ajub_asm_v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables thioesterase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K63-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of plasma membrane signaling receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TNF receptor-associated factor 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027475565.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VMU_Ajub_asm_v1.0

Genomic

  1. NC_069395.1 Reference VMU_Ajub_asm_v1.0

    Range
    36863348..36914693
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027074492.2 → XP_026930293.1  TNF receptor-associated factor 5 isoform X1

    UniProtKB/TrEMBL
    A0A6J2ALL6
    Conserved Domains (4) summary
    COG0419
    Location:239 → 400
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    cd03780
    Location:404 → 551
    MATH_TRAF5; Tumor Necrosis Factor Receptor (TNFR)-Associated Factor (TRAF) family, TRAF5 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of ...
    pfam02176
    Location:128 → 183
    zf-TRAF; TRAF-type zinc finger
    cd16642
    Location:39 → 94
    mRING-HC-C3HC3D_TRAF5; Modified RING finger, HC subclass (C3HC3D-type), found in tumor necrosis factor (TNF) receptor-associated factor 5 (TRAF5) and similar proteins

  2. XM_027074491.2 → XP_026930292.1  TNF receptor-associated factor 5 isoform X1

    UniProtKB/TrEMBL
    A0A6J2ALL6
    Conserved Domains (4) summary
    COG0419
    Location:239 → 400
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    cd03780
    Location:404 → 551
    MATH_TRAF5; Tumor Necrosis Factor Receptor (TNFR)-Associated Factor (TRAF) family, TRAF5 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of ...
    pfam02176
    Location:128 → 183
    zf-TRAF; TRAF-type zinc finger
    cd16642
    Location:39 → 94
    mRING-HC-C3HC3D_TRAF5; Modified RING finger, HC subclass (C3HC3D-type), found in tumor necrosis factor (TNF) receptor-associated factor 5 (TRAF5) and similar proteins

  3. XM_027074493.2 → XP_026930294.1  TNF receptor-associated factor 5 isoform X2

    UniProtKB/TrEMBL
    A0A6J2AP24
    Conserved Domains (4) summary
    COG0419
    Location:184 → 345
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    cd03780
    Location:349 → 496
    MATH_TRAF5; Tumor Necrosis Factor Receptor (TNFR)-Associated Factor (TRAF) family, TRAF5 subfamily, TRAF domain, C-terminal MATH subdomain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of ...
    pfam02176
    Location:128 → 186
    zf-TRAF; TRAF-type zinc finger
    cd16642
    Location:39 → 94
    mRING-HC-C3HC3D_TRAF5; Modified RING finger, HC subclass (C3HC3D-type), found in tumor necrosis factor (TNF) receptor-associated factor 5 (TRAF5) and similar proteins
Nucleotide Protein
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