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mthfd1b methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b [ Poecilia mexicana ]

Gene ID: 106913912, updated on 13-Mar-2024

Summary

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Gene symbol
mthfd1b
Gene description
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b
See related
Ensembl:ENSPMEG00000005969
Gene type
protein coding
RefSeq status
MODEL
Organism
Poecilia mexicana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Poecilia
Also known as
mthfd1
Orthologs
zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
28
Annotation release Status Assembly Chr Location
100 current P_mexicana-1.0 (GCF_001443325.1) Unplaced Scaffold NW_015094613.1 (245113..255633)

NW_015094613.1Genomic Context describing neighboring genes Neighboring gene kelch like family member 28 Neighboring gene chromosome unknown C14orf28 homolog Neighboring gene uncharacterized LOC106913917 Neighboring gene uncharacterized protein C15orf52 homolog

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015094613.1 Unplaced Scaffold Reference P_mexicana-1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables formate-tetrahydrofolate ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methenyltetrahydrofolate cyclohydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
C-1-tetrahydrofolate synthase, cytoplasmic
Names
methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Poecilia mexicana Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P_mexicana-1.0

Genomic

  1. NW_015094613.1 Reference P_mexicana-1.0

    Range
    245113..255633
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014980356.1 → XP_014835842.1  C-1-tetrahydrofolate synthase, cytoplasmic

    UniProtKB/TrEMBL
    A0A3B3Y9E3
    Related
    ENSPMEP00000023977.1, ENSPMET00000008829.1
    Conserved Domains (4) summary
    cd01080
    Location:119 → 291
    NAD_bind_m-THF_DH_Cyclohyd; NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase
    PLN02759
    Location:305 → 934
    PLN02759; Formate--tetrahydrofolate ligase
    COG0190
    Location:4 → 293
    FolD; 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme transport and metabolism]
    pfam00763
    Location:5 → 124
    THF_DHG_CYH; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
Nucleotide Protein
Heading Accession and Version

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