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TIAM2 TIAM Rac1 associated GEF 2 [ Sturnus vulgaris (Common starling) ]

Gene ID: 106859041, updated on 13-Mar-2024

Summary

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Gene symbol
TIAM2
Gene description
TIAM Rac1 associated GEF 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Sturnus vulgaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Sturnidae; Sturnus
Orthologs
human mouse all
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Genomic context

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See TIAM2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
30
Annotation release Status Assembly Chr Location
100 current Sturnus_vulgaris-1.0 (GCF_001447265.1) Unplaced Scaffold NW_014650670.1 (993966..1106026, complement)

NW_014650670.1Genomic Context describing neighboring genes Neighboring gene NADPH oxidase 3 Neighboring gene transcription factor B1, mitochondrial Neighboring gene claudin 20 Neighboring gene SR-related CTD associated factor 8 Neighboring gene CNKSR family member 3 Neighboring gene interaction protein for cytohesin exchange factors 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_014650670.1 Unplaced Scaffold Reference Sturnus_vulgaris-1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
T-lymphoma invasion and metastasis-inducing protein 2
Names
T cell lymphoma invasion and metastasis 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sturnus vulgaris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sturnus_vulgaris-1.0

Genomic

  1. NW_014650670.1 Reference Sturnus_vulgaris-1.0

    Range
    993966..1106026 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014886009.1 → XP_014741495.1  T-lymphoma invasion and metastasis-inducing protein 2 isoform X1

    Conserved Domains (6) summary
    cd00992
    Location:911 → 994
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd01230
    Location:506 → 632
    PH1_Tiam1_2; T-lymphoma invasion and metastasis 1 and 2 Pleckstrin Homology (PH) domain, N-terminal domain
    cd01255
    Location:1316 → 1488
    PH2_Tiam1_2; T-lymphoma invasion and metastasis 1 and 2 Pleckstrin Homology (PH) domain, C-terminal domain
    pfam00169
    Location:508 → 621
    PH; PH domain
    pfam00621
    Location:1125 → 1314
    RhoGEF; RhoGEF domain
    cl00155
    Location:834 → 909
    UBQ; Ubiquitin-like proteins

  2. XM_014886010.1 → XP_014741496.1  T-lymphoma invasion and metastasis-inducing protein 2 isoform X1

    Conserved Domains (6) summary
    cd00992
    Location:911 → 994
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd01230
    Location:506 → 632
    PH1_Tiam1_2; T-lymphoma invasion and metastasis 1 and 2 Pleckstrin Homology (PH) domain, N-terminal domain
    cd01255
    Location:1316 → 1488
    PH2_Tiam1_2; T-lymphoma invasion and metastasis 1 and 2 Pleckstrin Homology (PH) domain, C-terminal domain
    pfam00169
    Location:508 → 621
    PH; PH domain
    pfam00621
    Location:1125 → 1314
    RhoGEF; RhoGEF domain
    cl00155
    Location:834 → 909
    UBQ; Ubiquitin-like proteins

  3. XM_014886012.1 → XP_014741498.1  T-lymphoma invasion and metastasis-inducing protein 2 isoform X3

    Conserved Domains (2) summary
    cd01255
    Location:219 → 391
    PH2_Tiam1_2; T-lymphoma invasion and metastasis 1 and 2 Pleckstrin Homology (PH) domain, C-terminal domain
    pfam00621
    Location:28 → 217
    RhoGEF; RhoGEF domain

  4. XM_014886011.1 → XP_014741497.1  T-lymphoma invasion and metastasis-inducing protein 2 isoform X2

    Conserved Domains (2) summary
    cd01255
    Location:280 → 452
    PH2_Tiam1_2; T-lymphoma invasion and metastasis 1 and 2 Pleckstrin Homology (PH) domain, C-terminal domain
    pfam00621
    Location:89 → 278
    RhoGEF; RhoGEF domain
Nucleotide Protein
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