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PTPN13 protein tyrosine phosphatase non-receptor type 13 [ Sturnus vulgaris (Common starling) ]

Gene ID: 106855709, updated on 13-Mar-2024

Summary

Gene symbol
PTPN13
Gene description
protein tyrosine phosphatase non-receptor type 13
Gene type
protein coding
RefSeq status
MODEL
Organism
Sturnus vulgaris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Sturnidae; Sturnus
Orthologs
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Genomic context

Location:
chromosome: Un
Exon count:
50
Annotation release Status Assembly Chr Location
100 current Sturnus_vulgaris-1.0 (GCF_001447265.1) Unplaced Scaffold NW_014650583.1 (768849..879784)

NW_014650583.1Genomic Context describing neighboring genes Neighboring gene Rho GTPase activating protein 24 Neighboring gene mitogen-activated protein kinase 10 Neighboring gene ALF transcription elongation factor 1 Neighboring gene uncharacterized LOC106855699

Genomic regions, transcripts, and products

Genomic Sequence:
NW_014650583.1 Unplaced Scaffold Reference Sturnus_vulgaris-1.0

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol 3-kinase regulatory subunit binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in peptidyl-tyrosine dephosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
tyrosine-protein phosphatase non-receptor type 13

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sturnus vulgaris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sturnus_vulgaris-1.0

Genomic

  1. NW_014650583.1 Reference Sturnus_vulgaris-1.0

    Range
    768849..879784
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014880584.1XP_014736070.1  tyrosine-protein phosphatase non-receptor type 13 isoform X1

    Conserved Domains (10) summary
    smart00194
    Location:22532505
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00228
    Location:15081599
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:574782
    B41; Band 4.1 homologues
    smart00750
    Location:3186
    KIND; kinase non-catalytic C-lobe domain
    cd00047
    Location:22792505
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00992
    Location:17931872
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00373
    Location:669782
    FERM_M; FERM central domain
    pfam09379
    Location:577639
    FERM_N; FERM N-terminal domain
    pfam16599
    Location:11811371
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl17171
    Location:778878
    PH-like; Pleckstrin homology-like domain
  2. XM_014880585.1XP_014736071.1  tyrosine-protein phosphatase non-receptor type 13 isoform X2

    Conserved Domains (10) summary
    smart00194
    Location:22522504
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00228
    Location:15081599
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:574782
    B41; Band 4.1 homologues
    smart00750
    Location:3186
    KIND; kinase non-catalytic C-lobe domain
    cd00047
    Location:22782504
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00992
    Location:17931872
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00373
    Location:669782
    FERM_M; FERM central domain
    pfam09379
    Location:577639
    FERM_N; FERM N-terminal domain
    pfam16599
    Location:11811371
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl17171
    Location:778878
    PH-like; Pleckstrin homology-like domain
  3. XM_014880586.1XP_014736072.1  tyrosine-protein phosphatase non-receptor type 13 isoform X3

    Conserved Domains (10) summary
    smart00194
    Location:22482500
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00228
    Location:15031594
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:574782
    B41; Band 4.1 homologues
    smart00750
    Location:3186
    KIND; kinase non-catalytic C-lobe domain
    cd00047
    Location:22742500
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00992
    Location:17881867
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00373
    Location:669782
    FERM_M; FERM central domain
    pfam09379
    Location:577639
    FERM_N; FERM N-terminal domain
    pfam16599
    Location:11811371
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl17171
    Location:778878
    PH-like; Pleckstrin homology-like domain
  4. XM_014880587.1XP_014736073.1  tyrosine-protein phosphatase non-receptor type 13 isoform X4

    Conserved Domains (10) summary
    smart00194
    Location:22212473
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00228
    Location:14761567
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:542750
    B41; Band 4.1 homologues
    smart00750
    Location:3186
    KIND; kinase non-catalytic C-lobe domain
    cd00047
    Location:22472473
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00992
    Location:17611840
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00373
    Location:637750
    FERM_M; FERM central domain
    pfam09379
    Location:545607
    FERM_N; FERM N-terminal domain
    pfam16599
    Location:11491339
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl17171
    Location:746846
    PH-like; Pleckstrin homology-like domain
  5. XM_014880588.1XP_014736074.1  tyrosine-protein phosphatase non-receptor type 13 isoform X5

    Conserved Domains (9) summary
    smart00194
    Location:20142266
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00228
    Location:12691360
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:335543
    B41; Band 4.1 homologues
    cd00047
    Location:20402266
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00992
    Location:15541633
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00373
    Location:430543
    FERM_M; FERM central domain
    pfam09379
    Location:338400
    FERM_N; FERM N-terminal domain
    pfam16599
    Location:9421132
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl17171
    Location:539639
    PH-like; Pleckstrin homology-like domain