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HNF1A HNF1 homeobox A [ Equus asinus (ass) ]

Gene ID: 106844803, updated on 13-Mar-2024

Summary

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Gene symbol
HNF1A
Gene description
HNF1 homeobox A
See related
Ensembl:ENSEASG00005004491
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus asinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
11
Annotation release Status Assembly Chr Location
101 current ASM1607732v2 (GCF_016077325.2) 8 NC_052184.1 (37757048..37779620, complement)
100 previous assembly ASM130575v1 (GCF_001305755.1) Unplaced Scaffold NW_014638259.1 (1773349..1802807)

Chromosome 8 - NC_052184.1Genomic Context describing neighboring genes Neighboring gene 2'-5'-oligoadenylate synthase-like protein 2 Neighboring gene chromosome 8 C12orf43 homolog Neighboring gene 2'-5'-oligoadenylate synthetase like Neighboring gene uncharacterized LOC123288035 Neighboring gene glycine-rich protein DOT1-like Neighboring gene signal peptide peptidase like 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in insulin secretion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in liver development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in pancreas development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hepatocyte nuclear factor 1-alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus asinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1607732v2

Genomic

  1. NC_052184.1 Reference ASM1607732v2

    Range
    37757048..37779620 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014862474.2 → XP_014717960.1  hepatocyte nuclear factor 1-alpha isoform X1

    UniProtKB/TrEMBL
    A0A8C4L9C0
    Related
    ENSEASP00005006192.2, ENSEAST00005006775.2
    Conserved Domains (4) summary
    cd00086
    Location:200 → 273
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
    pfam04813
    Location:542 → 630
    HNF-1A_C; Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus
    pfam04812
    Location:282 → 540
    HNF-1B_C; Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus
    pfam04814
    Location:8 → 167
    HNF-1_N; Hepatocyte nuclear factor 1 (HNF-1), N terminus

  2. XM_044775749.1 → XP_044631684.1  hepatocyte nuclear factor 1-alpha isoform X2

    Conserved Domains (2) summary
    PHA03247
    Location:183 → 454
    PHA03247; large tegument protein UL36; Provisional
    cd00086
    Location:83 → 156
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
Nucleotide Protein
Heading Accession and Version

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