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MERTK MER proto-oncogene, tyrosine kinase [ Equus asinus (ass) ]

Gene ID: 106838544, updated on 11-Apr-2024

Summary

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Gene symbol
MERTK
Gene description
MER proto-oncogene, tyrosine kinase
See related
Ensembl:ENSEASG00005006464
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus asinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
19
Annotation release Status Assembly Chr Location
101 current ASM1607732v2 (GCF_016077325.2) 6 NC_052182.1 (77954690..78056639, complement)
100 previous assembly ASM130575v1 (GCF_001305755.1) Unplaced Scaffold NW_014638070.1 (2149295..2253475)

Chromosome 6 - NC_052182.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123286699 Neighboring gene fibulin 7 Neighboring gene transmembrane protein 87B Neighboring gene anaphase promoting complex subunit 1 Neighboring gene putative speedy protein E7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phagocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase Mer

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus asinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1607732v2

Genomic

  1. NC_052182.1 Reference ASM1607732v2

    Range
    77954690..78056639 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014852720.2 → XP_014708206.1  tyrosine-protein kinase Mer

    UniProtKB/TrEMBL
    A0A8C4PJ80
    Related
    ENSEASP00005009031.2, ENSEAST00005009836.2
    Conserved Domains (6) summary
    cd05749
    Location:199 → 279
    Ig2_Tyro3_like; Second immunoglobulin (Ig)-like domain of Axl/Tyro3 receptor tyrosine kinases (RTKs)
    smart00410
    Location:100 → 193
    IG_like; Immunoglobulin like
    cd00063
    Location:284 → 378
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14204
    Location:579 → 862
    PTKc_Mer; Catalytic Domain of the Protein Tyrosine Kinase, Mer
    pfam00047
    Location:104 → 176
    ig; Immunoglobulin domain
    pfam07714
    Location:587 → 854
    Pkinase_Tyr; Protein tyrosine kinase
Nucleotide Protein
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