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HCK HCK proto-oncogene, Src family tyrosine kinase [ Equus asinus (ass) ]

Gene ID: 106833726, updated on 11-Apr-2024

Summary

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Gene symbol
HCK
Gene description
HCK proto-oncogene, Src family tyrosine kinase
See related
Ensembl:ENSEASG00005003725
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus asinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 15
Exon count:
14
Annotation release Status Assembly Chr Location
101 current ASM1607732v2 (GCF_016077325.2) 15 NC_052191.1 (23162716..23202506)
100 previous assembly ASM130575v1 (GCF_001305755.1) Unplaced Scaffold NW_014637956.1 (2169138..2210521)

Chromosome 15 - NC_052191.1Genomic Context describing neighboring genes Neighboring gene XK related 7 Neighboring gene CCM2 like scaffold protein Neighboring gene transmembrane 9 superfamily member 4 Neighboring gene uncharacterized LOC123277134 Neighboring gene putative testis-specific Y-encoded-like protein 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase HCK

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus asinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1607732v2

Genomic

  1. NC_052191.1 Reference ASM1607732v2

    Range
    23162716..23202506
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044748388.1 → XP_044604323.1  tyrosine-protein kinase HCK isoform X2

    Conserved Domains (3) summary
    cd10363
    Location:117 → 220
    SH2_Src_HCK; Src homology 2 (SH2) domain found in HCK
    cl17036
    Location:59 → 114
    SH3; Src Homology 3 domain superfamily
    cl21453
    Location:227 → 341
    PKc_like; Protein Kinases, catalytic domain

  2. XM_014845051.2 → XP_014700537.1  tyrosine-protein kinase HCK isoform X1

    UniProtKB/TrEMBL
    A0A8C4PH27
    Related
    ENSEASP00005005020.2, ENSEAST00005005492.2
    Conserved Domains (4) summary
    cd10363
    Location:117 → 220
    SH2_Src_HCK; Src homology 2 (SH2) domain found in HCK
    pfam07714
    Location:239 → 488
    Pkinase_Tyr; Protein tyrosine kinase
    cl17036
    Location:59 → 114
    SH3; Src Homology 3 domain superfamily
    cl21453
    Location:231 → 501
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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